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Impact of Environmental Exposures on Tumor Risk in Subjects at Risk of Hereditary SDHx Paraganglioma — PGL-EXPO-1  

Genetic Predisposition Clinical Trial

Official title:
Impact of Environmental Exposures on Tumor Risk in Subjects at Risk of Hereditary SDHx-related Paragangliomas, Pilot Phase

Clinical Trial Summary

The main objective of the pilot phase of PGLEXPO will be to assess the faisability and to precise methodology of a case-control study designed for testing the impact of environmental and professional exposures on the tumoral risk in SDHx-mutation carriers

Clinical Trial Description

The main objective of the pilot phase of PGLEXPO will be to assess the faisability and to precise methodology of a case-control study designed for testing the impact of environmental and professional exposures on the tumoral risk in SDHx-mutation carriers. Patients will be selected from subjects with a mutation in one of the SDHx genes. The cases will have developed a tumor, while the controls will be tumor-free. Controls will be matched to the cases according to sex, age and type of gene affected. Past exposures will be sought through a telephone questionnaire. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04481152
Study type Observational
Source Assistance Publique - Hôpitaux de Paris
Contact Anne-Paule GIMENEZ-ROQUEPLO, MD, PhD
Phone 33 1 56 09 38 81
Email anne-paule.gimenez-roqueplo@aphp.fr
Status Not yet recruiting
Phase
Start date March 1, 2022
Completion date September 1, 2022
View Details
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