Low Flow Anaesthesia, is There a Difference Between 2 Modern Anaesthetic Machines Using Different Gas Reservoir

General Anaesthesia Clinical Trial

— LF  

Official title:

Low Flow Anaesthesia; Cost-effectiveness of the Flow-I Anaesthesia Machine, a Comparison to Established Anaesthesia Delivery Unit

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT02013869
• Other study ID #: 201301
• Secondary ID: JJ201301
• Status: Terminated
• Phase: N/A
• Start date: May 2015
• Est. completion date: August 2017

Study information

• Verified date: March 2024
• Source: Karolinska Institutet
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To study the Flow-I breathing circle during low flow general anaesthesia, whether this non-below system has advantages reduced time to reach Et 1MAC (minimal alveolar concentration) and lower consumption of inhaled agent

Description:

Assessing whether there are clinical differences in anaesthetic performance between standard anaesthesia workstation including a below and the new Flow-I device without a below

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 40
• Est. completion date: August 2017
• Est. primary completion date: August 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

ASA 1-2 patient 18 - 65 years scheduled for elective surgery

Exclusion Criteria:

ASA > 2 heart failure COPD

Related Conditions & MeSH terms

• General Anaesthesia

Intervention

Device:
• Flow-I, a modern anaesthetic machine without a bag/below/gas reservoir for compression of insufflation gas
Desflurane Dialed setting 18 % on the machine gas vaporized
• Asys, a anaesthetic machine with a bag/bellow for compression of gas to be insufflated
Desflurane dialed 18% on the machine gas vaporized

Locations

Country	Name	City	State
Sweden	Danderyds Hospital	Stockholm

Sponsors (2)

Lead Sponsor	Collaborator
Jan Jakobsson	University of California, Irvine

Country where clinical trial is conducted

Sweden, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Adequate anaesthesia	Patients will be asked after end of anaesthesia if they have had any recall of intraoperative events	5 hours
Primary	Time to reach 1.5 MAC (minimal alveolar concentration) Et	The time needed, seconds, to increase the end tidal desflurane concentration during wash-in from a 1 MAC to a 1.5 MAC with a constant fresh gas flow of 1 L/min and the vaporiser set a 3 MAC ( minimal alveolar concentration) (18%) will be compared between the two study groups	1 hour
Secondary	amount of inhaled agent consumed ml/min	The vaporiser will be weighed before and after each case and the amount of vapor, desflurane, consumed during the anaesthesia will be calculated Gr/min.	5 hours
Secondary	Postoperative Quality of Recovery	Quality of recovery will be followed during the first 72 hours after anaesthesia	72 hours