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Gastric Reflux clinical trials

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NCT ID: NCT05500196 Recruiting - Gastric Reflux Clinical Trials

Impact of Gastric Length of Myotomy During POEM on Gastroesophageal Reflux

IGL
Start date: July 7, 2021
Phase:
Study type: Observational

This observational study will be conducted among 43 patients of both sexes in each group Study participants will be of the age more than 18 years - STUDY PROCEDURE-Pre-defined technique to avoid bias and confounding due to multiple factors - All the poem procedures will be performed by posterior route - Preservation of sling fibers will be attempted in all the cases to avoid heterogeneity - Length of esophageal myotomy will be kept constant (4-6cm) - Double scope technique will be utilized to confirm the gastric extent of myotomy First evaluation at 1-month: based on Symptoms • Second evaluation: at 6 months by - Objective evaluation: UGI endoscopy, High resolution manometry, Timed barium swallow - Eckardt score, GERD-HRQL - 24-hour pH study with manual readings

NCT ID: NCT05320796 Recruiting - Obesity Clinical Trials

The Bioavailability and Effect on Pouch pH of Esomeprazole After Gastric Bypass

Start date: November 1, 2023
Phase: Phase 4
Study type: Interventional

The objective of this study is to investigate the effect of Esomeprazol administered in tablets (Esomeprazol MUT Sandoz® 40mg) or in solution (Esomeprazol MUT Sandoz® 40mg in 10ml tap water) on acid production in the gastric pouch by measuring the intragastric pH and the serum concentration of esomeprazole.

NCT ID: NCT05060744 Recruiting - Gastric Reflux Clinical Trials

Efficacy and Speed of Action of a Product to Control Gastric Hydration and Gastroesophageal Reflux

AQUAA
Start date: September 9, 2021
Phase: N/A
Study type: Interventional

A Randomised, Placebo-Controlled Clinical Trial off the Efficacy and Rapidity of Action of a Product Containing Sodium Alginate, Calcium and Magnesium Salts, Hyaluronic Acid and Aloe Vera to Control Oesophageal-Gastric pH and Reduce Symptoms of Gastric Reflux and Hyperacidity.

NCT ID: NCT05016076 Withdrawn - Obesity Clinical Trials

Multi-Strategy Intervention for Anesthesia Care of Obese Patients A Factorial Randomized Controlled Trial

Start date: May 2022
Phase: N/A
Study type: Interventional

The main objective of this study is to investigate the optimal anesthesia for obese patients undergoing bariatric surgery in the strategies of positive pulmonary ventilation, tracheal intubation technique, hemodynamic monitoring, and postoperative nausea and vomiting (PONV) prophylaxis, as the followed: 1. To evaluate the effectiveness and adverse effect of intravenous dexamethasone for PONV prophylaxis 2. To determine the safe inspiratory pressure to prevent the occurrence of gastric insufflation during facemask ventilation using point-of-care ultrasonography of antrum 3. To compare the effectiveness and safety between video intubating stylet and video laryngoscope in the placement of tracheal tubes 4. To apply minimally invasive CO monitors in guiding goal-directed hemodynamic therapy and assess its impact on major complications and postoperative recovery

NCT ID: NCT04105894 Not yet recruiting - Clinical trials for Gastro Esophageal Reflux

Gastric Reflux and Sinonasal Symptoms

Start date: January 2020
Phase:
Study type: Observational

The study is conducted to: - study correlation between sinonasal troubles & GERD - Assess whether antireflux therapy improve state of sinus in patients complaining from reflux & sinonasal symptoms