A Trial to Evaluate Para-aortic Lymphadenectomy for Gastric Cancer

Status Completed

Clinical Trial Summary

To evaluate the survival benefit of para-aortic lymphadenectomy in potentially curative gastrectomy

Clinical Trial Description

Radical gastrectomy with regional lymphadenectomy is the only curative treatment option for gastric cancer. The extent of lymphadenectomy, however, is controversial. The two European randomized trials only reported an increase in operative morbidity and mortality, but failed to show survival benefit, in the D2 lymphadenectomy group. We conducted a randomized controlled trial to compare the Japanese standard D2 and D2 + para-aortic nodal dissection. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00149279
Study type	Interventional
Source	Japan Clinical Oncology Group
Contact
Status	Completed
Phase	Phase 3
Start date	July 1995
Completion date	April 2006

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