Gastric Cancer Patients Undergoing Laparoscopic Gastrectomy Clinical Trial
| Verified date | May 2015 |
| Source | Yonsei University |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | Korea: Institutional Review Board |
| Study type | Interventional |
The investigators hypothesized that sympatholytic effect of dexmedetomidine would attenuate the hemodynamic instability and decrease in the splanchnic blood flow caused by pneumoperitoneum during laparoscopic surgery. This study is to investigate the effect of intraoperative dexmedetomidine infusion on postoperative bowel movement in patients undergoing laparoscopic gastrectomy.
| Status | Completed |
| Enrollment | 92 |
| Est. completion date | January 2015 |
| Est. primary completion date | January 2015 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 20 Years to 70 Years |
| Eligibility |
Inclusion Criteria: - patient between 20 and 65 of age with ASA physical status ?-? - gastric cancer patient undergoing laparoscopic gastrectomy Exclusion Criteria: - ASA physical status ? - bradycardia (< 60 bpm), arrhythmia - uncompensated heart failure - hepatic failure (Child-Pugh score B ??) - renal failure (eGFR MDRD < 60 ml/min/1.73m2) |
Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Outcomes Assessor)
| Country | Name | City | State |
|---|---|---|---|
| Korea, Republic of | Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, | Seoul |
| Lead Sponsor | Collaborator |
|---|---|
| Yonsei University |
Korea, Republic of,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Other | soft diet time | To evaluate the postoperative bowel movement, we will assess the time to resume soft diet intake | up to 1 week | No |
| Primary | gas passing | To evaluate the postoperative bowel movement, we will assess the time to first gas passing | up to 1 week | No |
| Secondary | sips of water time | To evaluate the postoperative bowel movement, we will assess the time to resume water intake | up to 1 week | No |