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Gallstones clinical trials

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NCT ID: NCT01972620 Completed - Pain Clinical Trials

RCT: Multi-modal Analgesia for Laparoscopic Cholecystectomy

LapChole
Start date: February 2010
Phase: N/A
Study type: Interventional

Analgesic efficacy of multi-modal analgesia is superior to standard analgesia for patients undergoing elective laparoscopic cholecystectomy for symptomatic cholelithiasis. Topical cystic plate and port-site incision 0.25% bupivacaine significantly reduces pain after laparoscopic cholecystectomy.

NCT ID: NCT01881399 Completed - Cholelithiasis Clinical Trials

Fluorescence Versus Intraoperative Cholangiography in the Visualization of Biliary Tree Anatomy

FLARIOC
Start date: November 2013
Phase: N/A
Study type: Interventional

The burden of iatrogenic bile duct injury (BDI), the most feared complication of laparoscopic cholecystectomy (LC), is extremely high and the repercussions on the patient's outcomes may be severe ranging from intraoperative repair to liver transplant or patient's death. Different techniques have been proposed to prevent BDI. Our hypothesis is that a fluorescence-based Imaging would allow visualization of the biliary tree anatomy as good as with the Intraoperative Cholangiogram with several main advantages: 1. ease of use 2. lack of invasiveness 3. absence of ionizing radiation to the patient and the operating staff 4. performed prior to any dissection (prior to "critical view of safety") Capacity of enhanced-reality based on virtual cholangiography (computer treatment of MRI images) to guide biliary tree anatomy visualization will be also evaluated in this study. The study requires a 2-month patient participation.

NCT ID: NCT01873638 Completed - Gallstone Disease Clinical Trials

Comparing Minilaparotomy and Laparoscopic Cholecystectomy as a Day Surgery Procedure

Start date: February 2006
Phase: N/A
Study type: Interventional

Minlaparotomy (MC) and laparoscopic cholecystoctomy (LC) are commonly applied surgical techniques for the management of symptomatic gallstone disease and both techiques have shown to be feasible for day surgery. However, to our knowledge the long-term outcome between these approaches has not been compared in randomised trials as day surgery procedures.

NCT ID: NCT01855308 Completed - Cholelithiasis Clinical Trials

Single Site Robotic Cholecystectomy in Non Selected Patients

SSRC
Start date: January 2012
Phase: N/A
Study type: Observational

This is a study of new technology to allow gallbladder removal through a single small surgical incision. A surgical robot is utilized to help navigate the small space. In this study, patient characteristics are broad to assess how applicable the procedure is to everyone.

NCT ID: NCT01824186 Completed - Pancreatitis Clinical Trials

Trial Comparing Pain in Single-incision Laparoscopic Cholecystectomy Versus Conventional Laparoscopic Cholecystectomy

Start date: October 2010
Phase: N/A
Study type: Interventional

This study aims to evaluate post-operative pain in single-incision laparoscopic cholecystectomy (SILC) versus the conventional four port technique (LC). The investigators hypothesize that SILC is non-inferior in post-operative pain.

NCT ID: NCT01740973 Completed - Incisional Hernia Clinical Trials

Risk of Umbilical Trocar-site Hernia After SILC Cholecystectomy Versus Conventional Cholecystectomy

UMBI-SILS
Start date: April 2014
Phase: N/A
Study type: Observational

Background Laparoscopic cholecystectomy is a very common procedure. Postoperative pain, especially around the umbilical port is dominating the first postoperative week. Single Incision Laparoscopic cholecystectomy (SILC) has been proposed to diminish postoperative incisional pain and improve cosmetic results, but results are not convincing and the risk of formation of an umbilical trocar-site hernia is not properly investigated. This study aimed to investigate the risk of umbilical trocar-site hernia formation after SILC vs. conventional 4-port laparoscopic cholesystectomy. Methods This is a cohort registry study with prospective questionnaire and clinical follow-up on 239 patients having a SILC from 1/1 2009 to 1/6 2011 vs. 478 mathed patients having a conventional laparoscopic cholecystectomy (consecutively from one month before and after SILC. They are matched for age, gender, date of operation, and surgeons skills (database from intraoperatively registered data). Primary endpoint is umbilical trocar-site hernia formation (operation for a umbilical hernia or clinical hernia). The H0 hypothesis is that there is not difference between SILC and conventional. Exclusion criteria are: death, operation for acute cholecystitis. The included patients will be sent a questionnaire asking for operation for a hernia in the area, suspicion of a hernia, and perioperative data that we do not have in the database. Futhermore those patients who suspect a hernia will be invited to aclinical exam by a medic to state the diagnosis. Furthermore we patients are asked to report if they have chronic pain and/or discomfort.

NCT ID: NCT01734720 Completed - Clinical trials for Common Bile Duct Stone

Common Bile Duct Stones - Natural History and Interventions

Start date: May 2005
Phase: N/A
Study type: Observational

The aims of this study were to 1. investigate what measures were taken when common bile duct stones (CBDS) were found intraoperatively in Sweden during the period May 2005 to December 2009 by using data from this population-based nationwide registry, and 2. analyze the outcome in terms of complications and success rates of bile duct clearance in relation to various stone sizes and interventions used. In order to further characterize the natural course of CBDS of various sizes, particular interest was focused on patients with positive findings where no peroperative measures to clear the bile ducts were taken or planned postoperatively.

NCT ID: NCT01685775 Completed - Clinical trials for Laparoscopic Cholecystectomy

Needlescopic Versus Transvaginal/Transumbilical Cholecystectomy

NATCH
Start date: February 2010
Phase: N/A
Study type: Interventional

Laparoscopic surgery has become the golden standard for the removal of the gallbladder. Recently, developments have been made so that operations can be performed through a natural orifice instead of the abdominal wall, thus minimizing the trauma of a procedure. This study compares the transvaginal/transumbilical cholecystectomy with the laparoscopic operation using 2-3mm instruments in female patients. It also examines the benefits and disadvantages related to postoperative pain, cosmetic aspects, and potential physiological alterations to the transvaginal approach that affect sexual intercourse.

NCT ID: NCT01678391 Completed - Clinical trials for Common Bile Duct Gall Stones

Feasibility of Endoscopic Ultrasound Based Biliary Stone Removal Without Fluoroscopy

Start date: August 2012
Phase: N/A
Study type: Interventional

To assess the feasibility and success of endoscopic ultrasound (EUS) directed biliary stone removal without use of fluoroscopy. Success for this study will be defined as the successful removal of all stones from the bile duct without the use of fluoroscopy. Fluoroscopy will only be used at the end of a presumed successful procedure to confirm that all stones are removed.

NCT ID: NCT01667848 Completed - Cholecystolithiasis Clinical Trials

Warmed, Humidified Carbon Dioxide Insufflation vs Standard Carbon Dioxide in Laparoscopic Cholecystectomy

Start date: July 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effect of warmed, humidified carbon dioxide Insufflation vs standard carbon dioxide in laparoscopic cholecystectomy.