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Gallbladder Diseases clinical trials

View clinical trials related to Gallbladder Diseases.

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NCT ID: NCT05068739 Completed - Biliary Stricture Clinical Trials

Needle Knife Fistulotomy Versus Partial Ampullary Endoscopic Mucosal Resection for Difficult Biliary Cannulation

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

The aims of this study are to compare the needle knife fistulotomy (NKF) technique versus the partial ampullary endoscopic mucosal resection (PA-EMR) technique in patients with difficult biliary cannulation and to assess the incidence rate of complications between these cannulation methods.

NCT ID: NCT04922528 Not yet recruiting - Choledocholithiasis Clinical Trials

Visualization of the Extrahepatic biliaRy Tree Trial

VERT
Start date: August 2021
Phase: N/A
Study type: Interventional

This study is a prospective randomized controlled trial evaluating the use of a fluorescent dye, indocyanine green (ICG), in the identification of important bile duct anatomy during emergent same-admission cholecystectomy. Participants will be randomized into either the control arm, which uses the standard of care white light during laparoscopy or the intervention arm, which will use ICG fluorescent cholangiography as an adjunct to white light to visualize the biliary anatomy. The investigators hypothesize that the use of fluorescent cholangiography will increase the rates of identification of important biliary anatomy during laparoscopic cholecystectomy. The effectiveness, feasibility, and safety will be compared between the two groups using a post-operative survey form the surgeons will complete prior to exiting the operating room.

NCT ID: NCT04915651 Recruiting - Cholecystitis Clinical Trials

Gallbladder Cryoablation in High-Risk Patients

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

Benign gallbladder disease, including acute cholecystitis, chronic cholecystitis, biliary dyskinesia, and biliary colic, is very common, with over 300,000 surgical cholecystectomies performed per year in the US. Unfortunately, complication rates in elderly patients or patients with many comorbidities are high. These patients are often managed with percutaneous tube drainage of the gallbladder (percutaneous cholecystostomy). The recurrence rate of calculous cholecystitis after cholecystostomy tube removal is as high as 35% at 1 year. These patients are thus faced with permanent cholecystostomy tube drainage, high-risk surgery, or cholecystostomy tube removal and risk of repeat cholecystitis. Gallbladder cryoablation is an alternative to surgical cholecystectomy which is performed percutaneously and does not require general anesthesia. Published evidence on the outcomes of gallbladder cryoablation is however limited at this point in time. The purpose of the proposed study is to follow the outcomes of high-risk patients who undergo gallbladder cryoablation.

NCT ID: NCT04705740 Completed - Pancreatic Diseases Clinical Trials

Influence of the Endoscopists and Endoscopic Retrograde CholangioPanceratography

Start date: September 1, 2020
Phase:
Study type: Observational

Retrospective analysis on a prospective database that analyzes the influence of the number of endoscopists on the Endoscopic Retrograde CholangioPanceratography result.

NCT ID: NCT04582240 Completed - Surgery Clinical Trials

Bile Duct Injury Digestif

Start date: January 1, 2008
Phase:
Study type: Observational

Data accumulated from medical record collected from January 2008 until December 2018

NCT ID: NCT04563260 Completed - Clinical trials for Gallbladder Diseases

Effect of Palonosetron on Remifentanil for Preventing Emergence Cough in Female

Start date: October 7, 2020
Phase: N/A
Study type: Interventional

The primary purpose of this study is to investigate the optimal Ce of remifentanil for preventing emergence cough following extubation during general anesthesia in female patients who receive the palonosetron or not.

NCT ID: NCT04409652 Completed - Clinical trials for Gallbladder Diseases

Head Position on Preventing Emergence Cough

Start date: June 2, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effect of head position on prevent the emergence cough followed by endotracheal extubation.

NCT ID: NCT04407078 Completed - Clinical trials for Gallbladder Diseases

Sugammadex on Remifentanil Ce for Preventing Emergence Cough in Female

Start date: December 2, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the optimal Ce of remifentanil for preventing emergence cough following extubation during general anesthesia in female who are reversed with sugammadex or neostigmine.

NCT ID: NCT04368611 Completed - Laparoscopy Clinical Trials

Emergency Laparoscopic Cholecystectomy With Low Pressure Pneumo-peritoneum in Cardiopulmonary Risk Patients: Fundus First Cholecystectomy VS Calot First Cholecystectomy .

Start date: March 1, 2015
Phase: N/A
Study type: Interventional

Introduction: Laparoscopic cholecystectomy is the usual approach in dealing with cholithiasis that greatly replace open approach even in acute emergency gall bladder diseases. Laparoscopic approach has great advantages than open approach but the biliary injuries are higher in laparoscopic approach than open approach. Laparoscopic approach is condemned for many years in cardiopulmonary risk patients because of its adverse impacts on cardiopulmonary systems. Performing laparoscopic cholecystectomy with low pressure pneumoperitoneum may be effective in treatment of acute gall bladder disease but with fundus first approach than classical Calot first approach. Aim: compare between initial Fundus first cholecystectomy followed by Calot dissection VS Calot only cholecystectomy in Emergency laparoscopic cholecystectomy with low pressure pneumo-peritoneum in cardiopulmonary risk patients as regard intraoperative data and postoperative complications. Patients and methods: This study prospective randomized controlled study was conducted on 470 cases with acute cholecystitis, biliary colic, mucocele and pyocele of gall bladder in emergency general surgery department. Patients were divided into 2 groups, Group A: fundus first group (235cases) and Group B (235cases): classical Calot first approach.

NCT ID: NCT04324515 Recruiting - Clinical trials for Roux-en-Y Gastric Bypass

Randomized Trial Comparing Gastric Bypass With and Without Cholecystectomy

Start date: July 18, 2018
Phase: N/A
Study type: Interventional

The main objective of this pilot study is to show feasibility to collect peri-operative and postoperative clinical data of the study group of gastric bypass without cholecystectomy compared with the control group of gastric bypass with cholecystectomy. Our hypothesis is that the approach without cholecystectomy would be superior in terms of a decrease of perioperative adverse events and postoperative complications, as well as lenght of operation, lenght of hospital stay, overall costs with a very low risk of biliary complication in the follow up. These findings could be helpful to build a baseline for a future randomized controlled multicenter study allowing significance of these results and help orientate surgeons towards best surgical care of the gallbladder with confirmed absence of stones in the obese patient undergoing gastric bypass.