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Assessment of Gastric Motility on Funtional Dyspepsia and Joint Hypermobility Syndrome

Functional Dyspepsia Clinical Trial

Official title:
Assessment of Gastric Motility on Funtional Dyspepsia and Joint Hypermobility Syndrome

Clinical Trial Summary

Functional dyspepsia (FD) is defined as the presence of gastroduodenal symptoms in the absence of organic disease that is likely to explain the symptoms. Joint hypermobility (JH) refers to the increased passive or active movement of a joint beyond its normal range. Recent reports have highlighted the co-existence of FD with Ehlers-Danlos syndrome type III or hypermobility type (EDSIII). The association between FD and EDS III, and the underlying pathophysiological alterations, are poorly understood. We hypothesised that EDS III might influence gastroduodenal sensorimotor function, resulting in dyspeptic symptoms. Therefore, the aim of this study is to explore the impact of EDS III on gastric motility, nutrient tolerance and dyspeptic symptoms in patients with functional dyspepsia.Our aim is to study the prevalence of EDSIII in FD compared to healthy subjects (HS) and to study the impact of co-existing EDSIII on gastric motility, nutrient tolerance and dyspeptic symptoms in FD.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04279990
Study type Observational
Source Universitaire Ziekenhuizen Leuven
Contact
Status Completed
Phase
Start date July 4, 2014
Completion date November 1, 2016
View Details
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