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Frailty clinical trials

View clinical trials related to Frailty.

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NCT ID: NCT06133894 Completed - Sarcopenia Clinical Trials

Effect of Exercise-education Program PERMANENTO in Late Life

PERMANENTO
Start date: February 13, 2023
Phase: N/A
Study type: Interventional

The general aim of the present study is to create and empirically evaluate (RCT trial) an online education and exercise program (called PERMANENTO) to help older adults to understand the wider consequences of being active and offer them easy to follow exercise program inspired by developmental kinesiology.

NCT ID: NCT06130787 Recruiting - Clinical trials for Leukemia,Myeloid, Chronic

Value of Biological Age, in Addition to Individual Frailty, for Personalising the Management of Cancer Treated With Targeted Therapy

BIO-TIMER
Start date: November 17, 2023
Phase: N/A
Study type: Interventional

French prospective multicenter, open-label study involving newly diagnosed CML patients. Two assessments will be performed during the follow-up of these patients: individual frailty using geriatric tools and individual biological aging determined by DNA methylation analysis.

NCT ID: NCT06127680 Active, not recruiting - Frailty Clinical Trials

Brief Health Promotion Intervention for Older People in Mental Health

Start date: March 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to test the delivery of brief health promotion advice with supporting information leaflets as part of standard clinical consultation for older people attending a community mental health service The main questions it aims to answer are: 1. Is a brief health promotion intervention designed for primary care transferable and acceptable to older people attending acute community-based mental health services (Travers et al 2022) 2. Can older adults with ongoing mental health conditions be recruited and retained in the study 3. Will participants adhere to the health promotion intervention over a three-month period 4. Can evaluation data be collected from participants Eligible participants will be asked to: - participate in a brief health promotion (10 minutes) advice given by an advanced nurse practitioner (ANP) in mental health during a routine outpatient clinic/home visit - participants receive exercise and protein advice leaflets (laminated) - participants rehearse the exercise with the ANP - one-month follow-up by ANP to assess and promote adherence to the intervention Researchers will use a one-group pre-post test study to compare baseline data on physical and mental health outcomes to participants' outcomes at three-month follow-up (there is no control group).

NCT ID: NCT06121921 Not yet recruiting - Frailty Clinical Trials

RESTORE-TAVI Pilot

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

This is a pilot randomised control study assessing the feasibility and effectiveness of a perioperative multi-component intervention aimed at reducing adverse hospital events and improving functional outcomes in patients with acute decompensated aortic stenosis undergoing urgent transcatheter aortic valve implantation compared to standard care. The intervention will consist of physical rehabilitation, delirium prevention, nutritional supplementation and anaemia correction (where indicated). The primary objective is to determine the feasibility and safety of delivering this intervention Secondary objectives include investigating the impact on adverse hospital events such as hospital-acquired disability and post-TAVI delirium, and on health-related quality of life and functional recovery following TAVI.

NCT ID: NCT06117462 Not yet recruiting - CFS Clinical Trials

Frailty in Critical Care Unit's Patients

Start date: December 2023
Phase:
Study type: Observational

In the study ,investigator aim to evaluate the frailty syndrome in critically ill patients, in both young and old populations,to determine its imapct on outcome, and impact of ICU in fraility

NCT ID: NCT06115889 Recruiting - Clinical trials for Cognitive Impairment

Smart Taiko-Drum Playing for Older Adults With Cognitive Frailty

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

The objective of this randomised controlled feasibility trial is to evaluate the feasibility of the Smart Taiko Drum-playing intervention embedding the cognitive-motor dual-task training concept for older adults with cognitive frailty, and identify the preliminary efficacy of the intervention on cognitive and physical functions and frailty status.

NCT ID: NCT06113016 Recruiting - Clinical trials for Anatomic Stage III Breast Cancer AJCC v8

Prevention of Frailty With Fisetin and Exercise (PROFFi) in Breast Cancer Survivors

PROFFi
Start date: April 17, 2024
Phase: Phase 2
Study type: Interventional

This phase II trial tests how well fisetin and exercise works in preventing frailty in breast cancer survivors. Fisetin is a natural substance found in strawberries and other foods and is available as a nutritional supplement. Nutritional supplements may be useful in eliminating cells that have undergone a process called senescence. Senescence is when a cell ages and permanently stops dividing but does not die. Over time, large numbers of these cells build up in tissues throughout the body and can release harmful substances that cause inflammation and damage nearby healthy cells. Giving fisetin may eliminate senescent cells in patients with breast cancer undergoing physical activity.

NCT ID: NCT06107699 Recruiting - Aging Clinical Trials

The CHARM Study-Coordinating Transitions From Hospital for Older Adults With Fractures

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

Background: Fall-related injuries like fractures are on the rise among older adults in New Brunswick. These injuries can lead to hospitalization and adverse health effects. Moreover, transitions from acute care can be complicated and overwhelming, especially for patients and their families. Researching patient navigators as a means of enhancing inpatient care, while also ensuring successful transitions in care for patients, may have positive impacts and help older adults successfully age in place. Objective: This study seeks to investigate the effects of having support from patient navigators in helping older adults admitted to the Orthopedic Unit with a fracture. Specifically, the objectives are to investigate whether there are differences between patients with patient navigators and those patients receiving standard of care, regarding: the length of stay in acute care; healthcare utilization post-discharge; patient and family experience and satisfaction with care; and, healthcare provider experiences working with patient navigators. Methods: This study uses a mixed-method concurrent embedded design, in which the quantitative randomized control trial has an embedded qualitative component. Potential Benefits/Risks: This study is considered low risk. Potential benefits of this study include a better understanding of the impact of support from a patient navigator on inpatient care and patient transitions. This information will be used to inform the development of practical recommendations for policymakers and clinicians on how to enhance inpatient acute care and successful transitions for older adults.

NCT ID: NCT06104696 Recruiting - Clinical trials for Kidney Transplant; Complications

Comprehensive Geriatric Assessment in Kidney Transplantation

CoGeriaTx
Start date: January 2, 2020
Phase:
Study type: Observational

This observational study aims to analyze the results of comprehensive geriatric assessment and to monitor the development of functional status in geriatric kidney transplant candidates and recipients.

NCT ID: NCT06102967 Not yet recruiting - Frailty Clinical Trials

EEG Characteristics and Postoperative Delirium

Start date: November 1, 2023
Phase:
Study type: Observational

The goal of this [type of study: observational study ] is to [compare Energy differences in various bands of intraoperative electroencephalogram in elderly patients with postoperative delirium and non delirium.] in [describe participant population selected 69 patients who underwent laparoscopic radical surgery for colorectal cancer on a selective basis]. The main question[s] it aims to answer are: • [Is there any difference in the spectral range of EEG between POD patients and non POD patients] Participants will [Cognitive.•Postoperative delirium.•Preoperative weakness.]