A Study of the Intervention Effect of a Hybrid Exercise Program on Frail Elderly

Frail Elderly Syndrome Clinical Trial

Official title:

Hybrid Exercise Program is Frail Elderly Need: Effectiveness on the Physical Abilities and Clinical Assistance From White Box Modeling

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05832853
• Other study ID #: CCEE2018
• Status: Completed
• Phase: N/A
• Start date: May 20, 2018
• Est. completion date: January 30, 2019

Study information

• Verified date: April 2023
• Source: Northeast Normal University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The declining physical condition of frail elderly is becoming an ugent problem. Although the exercise intensity of Wu Qin Xi appears to be low, it is highly effective in the older individuals. Inspired by the characteristics and functions of Wu Qin Xi, we designed a brand new exercise intervention training program among frail older people, which incorporates Wu Qin Xi, strength exercises and endurance exercises to improve physical fitness, and even reverse the condition of frailty. Furthermore, to improve utility in clinical practice, we innovatively employed machine learning simulations to infer the condition of older adults and predict their level of frailty after the intervention.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 181
• Est. completion date: January 30, 2019
• Est. primary completion date: December 30, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 60 Years to 75 Years

Eligibility

Inclusion Criteria:

1. a Fried frailty phenotype score of 3-5 points;

2. could walk for at least 6 min without support;

3. had not been able to walk in the past year other training.

Exclusion Criteria:

1. people who have a past mental illness or serious psychological issues which make it difficult to obey orders;

2. people who have had neurological disorders within the last six months;

3. people who must regularly participate in other training programs during the study period;

4. people who struggle to walk normally due to significant muscle and skeletal injuries and continuous joint discomfort.

Related Conditions & MeSH terms

• Frail Elderly Syndrome

Intervention

Behavioral:
• Wu Qin Xi exercise
The training schedule for Wu Qin Xi consisted of two phases: the first phase lasted for eight weeks, while the second phase lasted for 16 weeks. In the first phase, Wu Qin Xi group was given twice repetitions of the intervention. The second phase consisted of three repetitions of the Wu Qin Xi group. Participants warmed up for 20 min prior to the intervention and cooled down for 10 min at the end.
• Wu Qin Xi, resistance training and endurance training
During the first 8 weeks, the training consists of learning and consolidating the movements of the Wu Qin Xi. In the second 16 weeks, participants perform a full set of movement exercises. Each resistance training session contained two lower-body exercises (seated calf raises and hip abduction) and three upper-body exercises (lateral pull downs, biceps curls, and triceps push downs) and two sets for each exercise. Endurance training is performed by continuous walking on an undisturbed indoor track for 15 min. Participants warmed up for 20 min prior to the intervention and cooled down for 10 min at the end.
• Resistance training and endurance training
Each resistance training session contained two lower-body exercises (seated calf raises and hip abduction) and three upper-body exercises (lateral pull downs, biceps curls, and triceps push downs) and three sets for each exercise. Endurance training is performed by continuous walking on an undisturbed indoor track for 30 min. Participants warmed up for 20 min prior to the intervention and cooled down for 10 min at the end.

Locations

Country	Name	City	State
China	Chinese Center of Exercise Epidemiology	Changchun	Jilin

Sponsors (1)

Lead Sponsor	Collaborator
Guang Yang, Prof. Dr.

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Assessing the endurance of frail older adults using the six-minute walk test	Assessment of endurance in frail older adults before and after intervention using the six-minute walk test	Month 6
Primary	Assessing the speed of frail older adults using the ten-meter maximum walk speed	Assessment of speed in frail older adults before and after intervention using ten-meter maximum walk speed.	Month 6
Primary	Using handgrip strength tests to assess strength in frail older adults.	Using handgrip strength tests to assess strength in frail older adults before and after intervention	Month 6
Primary	Assessment of balance in frail older adults using Time Up and Go Test.	Assessment of balance in frail older adults before and after intervention using Time Up and Go Test.	Month 6