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Fractures, Stress clinical trials

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NCT ID: NCT05414708 Recruiting - PTSD Clinical Trials

Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

Art therapy is used across the Military Health System for treatment of posttraumatic symptoms, but there is limited research on how art therapy is able to restore emotional expression and regulation in service members. This research hopes to learn about the effects of art therapy on emotional expression and regulation in service members as well as the neurological systems at work. If a participant chooses to be in this study, he or she will attend ten sessions over a period of twelve weeks. The first session will be an interview and self-assessment questionnaires to collect information on a variety of symptoms, experiences, and personality traits, and an MRI scan. During the MRI scan, participants will be asked to perform a task where they will be shown a series of neutral and negative images. The middle eight sessions will be one-hour art therapy sessions with a certified art therapist. The last session will consist of the same self-assessment questionnaires and another MRI scan.

NCT ID: NCT05402072 Recruiting - Hip Arthroscopy Clinical Trials

AMIC Compared With Microfracture for Focal Articular Cartilage Damage of the Hip

REPAIR
Start date: March 13, 2023
Phase: Phase 1
Study type: Interventional

This is a pilot multi-centre RCT of 40 patients (ages 18-55 years, inclusive) undergoing primary hip arthroscopy with a focal articular cartilage defect of the acetabulum to compare the effect of using autologous matrix-induced chondrogenesis (AMIC) in comparison to microfracture on hip function, health-related quality of life, hip pain, cartilage regeneration, health utility, and any adverse events at 2 years. Follow-up will occur at 6 weeks, 6 months, 12 months, 18 months, and 24 months post-surgery.

NCT ID: NCT05377931 Recruiting - COVID-19 Clinical Trials

Ocular and Cardiac Effects of Battle Ground

Start date: May 10, 2022
Phase:
Study type: Observational

Mobile battle ground games are widely used in various age groups, there are ocular and cardiac affection that may affect users of this type of action games.

NCT ID: NCT05367505 Recruiting - Mobility Limitation Clinical Trials

Titanium Fusion Implant in Combination With Trans-iliac Screws for Insufficiency Fractures of the Pelvis

TIKTIS
Start date: January 9, 2023
Phase: N/A
Study type: Interventional

Many approaches to the surgical treatment of OF-P have been tried, but no one method has stood out as particularly successful. The placement of three implants, including implants that could minimise motion in the sacroiliac joint through early fixation and long-term fusion of the sacroiliac joint, can prevent micromotion in the fracture and thereby improve the clinical outcome of OF-Ps. The iFuse-3D implant was shown to be safe and effective for chronic sacroiliac pain in non-osteoporotic patients. The primary aim is to assess the proportion of patients operated on using iFuse-3D in conjunction with transiliac-transsacral screws who regain pre-fracture mobility by the time of hospital discharge.

NCT ID: NCT05298956 Recruiting - Stress Reaction Clinical Trials

Brain Substrates for Cardiovascular Stress Physiology

Start date: March 14, 2022
Phase: N/A
Study type: Interventional

Transcranial infrared laser stimulation is a non-invasive neuromodulation technique. The study will examine the effect of transcranial infrared laser stimulation on cardiovascular and metabolic responses to stress.

NCT ID: NCT05186194 Recruiting - Vitamin d Clinical Trials

The Effect of Vitamin D and Calcium Supplementation on the Prevention of Stress Fractures.

Start date: September 30, 2021
Phase: N/A
Study type: Interventional

The main objective of this study is to find whether supplemental vitamin d and calcium can reduce the incidence of stress fractures in recruits. These high-risk recruits undergo intensive training which elevated bone turnover, which requires adequate level of vitamin D and calcium in order to support bone health. It is hypothesized that supplemental vitamin d and calcium will decrease the occurrence of stress fractures.

NCT ID: NCT04953702 Recruiting - Clinical trials for Subchondral Insufficiency Fracture

Study of the Associations Between Subchondral Insufficiency Fractures of the Knee and Pre-existing Health, Lifestyle, and/or Musculoskeletal Conditions

Start date: June 10, 2021
Phase:
Study type: Observational

This prospective cohort study is designed to investigate possible association(s) between subchondral insufficiency fractures (SIFKs) of the knee and pre-existing health, lifestyle, and/or musculoskeletal conditions. In doing so, this research may shed light on the underlying cause(s) of SIFKs. It is hypothesized that SIFKs of the knee are related to osteoarthritis, weak bone, and/or metabolic issues, rather than trauma.

NCT ID: NCT04847115 Recruiting - Metatarsal Fracture Clinical Trials

Treatment of Fifth Metatarsal Zone 3 Fractures

Start date: April 10, 2021
Phase: N/A
Study type: Interventional

The fifth metatarsal is one of the bones where stress fractures can occur. Current literature provides support for both operative and non-operative treatment, but is mostly based on retrospective studies. One small randomized controlled trial reported faster recovery in the surgery group, but this study is probably subject to selection bias as well as underpowered design. There is a need to strengthen the knowledge base regarding treatment of stress fractures in the fifth metatarsal. This study seeks to answer whether osteosynthesis with an intramedullar screw fixation gives faster painfree weight bearing compared to non-operative treatment with a walking boot.

NCT ID: NCT04840147 Recruiting - Clinical trials for Articular Cartilage Disorder of Knee

A Comparison of JointRep® and Microfracture in Repair of Cartilage Lesions on the Femoral Condyle or Trochlea,

JMAC
Start date: September 22, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to compare whether JointRep® plus microfracture is more effective than microfracture alone when treating symptomatic focal articular cartilage lesions in the knee (femoral condyles or trochlea).

NCT ID: NCT04530214 Recruiting - Stress Reaction Clinical Trials

Predictive Elements of Trauma and Its After-effects: Importance of the Quality of Neurobiological Response to Stress

LIFT-UP
Start date: November 4, 2020
Phase:
Study type: Observational

The neurobiological response to stress is an adaptive response allowing us to cope with the multiple aggressions of daily life. This response orchestrates the body's systemic reaction. The intensity of response to stress can modify the body's functioning, which implies a variety of fields where biomarkers may be isolated: immunity, psychology, neurophysiology, integrative physiology. When stress is too intense or prolonged, response to stress may become misfitted and deleterious. This study is based on the hypothesis that a severe physical or psychological trauma is associated with an intense and misfitted stress that is responsible from an undue immuno-inflammatory activation (through sympathetic activation). The result is a subinvasive state of systemic and tissue inflammation (low-noise inflammation), responsible for the mid-term deleterious consequences of the traumatic event. The objective of this study is to understand how the dysregulation of intense stress simultaneously generates an initial pathological state and an alteration of mid-term evolution (which is considered as a poor prognosis and/or as responsible for after-effects). The investigators wish to identify relevant biomarkers of the mechanisms activated during intense stress and influencing the immuno-inflammatory and epigenetic spheres with deleterious consequences on physiological and psychological functions.