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Foot Ulcer clinical trials

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NCT ID: NCT01608425 Recruiting - Diabetes Mellitus Clinical Trials

Ulcer Monitoring in Diabetes Mellitus

Telesaar
Start date: April 2011
Phase: Phase 2
Study type: Interventional

Telemedicine technology enables a direct and online text- and image communication in the treatment system from patient to the ulcer specialist. The technology is expected to have patient-related, economic and therapeutic benefits. The study is a substudy of a larger project entitled "Renewing Health", where also the economic and management aspects are highlighted. However, only few randomized prospective studies are conducted in this field. The purpose of the study is in a randomized prospective study, to assess the impact of the introduction of the telemedicine technology as consultation form between ulcer-nurses in the primary sector and the wound clinics at the hospitals in the region. It is assessed whether the technology can be adopted without incurring the patient a risk. The study aims to perform an impact analysis of the introduction of new technologies for telemedicine wound monitoring in the treatment of diabetic foot ulcers through different studies.

NCT ID: NCT01537016 Recruiting - Clinical trials for Diabetic Foot Ulcers

WOUNDCHEK™ Protease Status Point of Care (POC) Diagnostic Test on DFU

Start date: July 2013
Phase: N/A
Study type: Interventional

The purpose of this trial is to determine if wounds with elevated protease activity (EPA) treated with targeted interventions such as protease modulating therapies can improve clinical and economic outcomes. It is hypothesized that protease modulating dressings may provide significantly better clinical outcomes on EPA wounds over current standard of care.

NCT ID: NCT01342497 Recruiting - Diabetic Foot Ulcer Clinical Trials

Oral BBR-012 in the Treatment of Diabetic Foot Ulcers, Proof of Concept Study

BBR-012
Start date: July 2011
Phase: Phase 2
Study type: Interventional

The aim of this Clinical Proof of Principle study is to evaluate the effect of BBR-012 on the healing of complicated diabetic foot ulcers.

NCT ID: NCT01137903 Recruiting - Diabetic Foot Clinical Trials

Efficacy of Surgical Treatment of Osteomyelitis in Diabetic Foot Ulcers

Start date: April 2010
Phase: N/A
Study type: Interventional

Hypothesis:Surgical treatment of osteomyelitis in diabetic foot is more effective that medical treatment through antibiotherapy and leads wound healing in ulcers complicated with bone infection.Material and Methods: Randomized clinical trials which include two groups of patients (n=88), one receives medical treatment through antibiotherapy during 90 days and the other group receive conservative surgical treatment and antibiotics during 7 days after surgery. It will be studied differences between both groups in healing time, recidives, present and relationship of adverse events and outflow of quality of life related health .

NCT ID: NCT00859599 Recruiting - Clinical trials for Diabetic Foot Ulcers

Monochromatic Phototherapy on Diabetic Foot Ulcers

Start date: August 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of monochromatic phototherapy (Biolight®) on foot ulcers in diabetic patients, in comparison of placebo phototherapy as a complementary to standard diabetic foot ulcer therapy. The study initiated with a four week long Run In Period to eliminate spontaneous healing ulcer to be included. Treatment with monochromatic phototherapy (Biolight® or placebo) will be given locally, additional to standard care, three times weekly during the first four weeks and twice weekly the following sixteen weeks or until the ulcer is completely healed, according to a pre-determined treatment plan. The area of the ulcer will be measured once weekly for 20 weeks or until the ulcer is completely healed.

NCT ID: NCT00839865 Recruiting - Diabetic Foot Ulcer Clinical Trials

Trial of Herb Yuyang Ointment to Diabetic Foot Ulcer

Start date: November 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if dressing change with a kind of herb Yuyang ointment is clinically more efficacious and safer than Conventional treatment in the treatment of diabetic foot ulcers.

NCT ID: NCT00475202 Recruiting - Clinical trials for Diabetic Foot Ulcers

Hyperbaric Oxygen Therapy and Angiogenesis in Diabetic Patients With Foot Ulcers

Start date: n/a
Phase: N/A
Study type: Observational

Diabetic foot ulcers are a major cause of morbidity and mortality, accounting for approximately two-thirds of all non-traumatic amputations performed in the United States. The cost of foot ulcers in diabetic patients averages almost $28,000 for the two years after diagnosis of the ulcer. Hyperbaric oxygen (HBO) serves as primary or adjunctive therapy for a diverse range of medical conditions. HBO also has been used as an adjunct to antibiotics, debridement, and revascularization in the therapy of chronic, nonhealing wounds associated with diabetes or non-diabetic vascular insufficiency. The aim of the study is to assess whether hyperoxia induced angiogenesis in diabetic patients with foot ulcers.

NCT ID: NCT00366132 Recruiting - Clinical trials for Chronic Diabetic Foot Ulcers

Safety & Efficacy Study for the Use of Extracorporeal Shockwaves in the Treatment of Diabetic Foot Ulcers

Start date: March 2006
Phase: Phase 2
Study type: Interventional

The purpose of this clinical study is to compare the safety and effectiveness of shockwave treatment combined with standard-of-care treatment, to standard-of-care treatment alone to induce healing of a chronic plantar foot ulcer in subjects with diabetes mellitus. For the purpose of this study, the definition of plantar foot ulcer is a wound or open sore that involves the plantar(bottom) aspect of the foot, and the definition of chronic is a duration of 6 weeks or greater with a lack of response to treatment.

NCT ID: NCT00330265 Recruiting - Diabetes Clinical Trials

Safety and Efficacy Study of an Interactive Wound Dressing (KC002) for the Treatment of Diabetic Foot Ulcers

KC-002PT
Start date: January 2006
Phase: Phase 2
Study type: Interventional

The objective of this study is to determine the safety and effectiveness of a device (the KC-002 interactive wound dressing) in the promotion of healing in diabetic foot ulcers as compared with a conventional wound therapy regimen for subjects with Type 1 or Type 2 diabetes mellitus. This is a prospective, randomized, multi-center, unmasked, controlled study. All patients will receive care for the diabetic foot ulcer during the study. Participation in the study is for 24 weeks.