Clinical Trials Logo
  1. Home
  2. Folic Acid Deficiency
  3. NCT02373033

Folate-Rich Foods Improve Folate Status — Folatefood  

Folic Acid Deficiency Clinical Trial

Official title:
The Effects of a 3-months Dietary Intervention With Folate Enhanced Foods on Folate Status in Healthy Egyptian Women

Clinical Trial Summary

This study evaluates the effects of folate-rich foods regarding improvement of folate status compared with folic acid supplement. A randomized, parallel intervention trial with two active groups (folate-rich foods or folic acid supplement) and one control group (apple juice - 0 µg/d folate) was executed over 12 weeks.

Clinical Trial Description

Sixty-two women in reproductive age, apparently healthy, non-smokers, not consuming special diets (vegetarian), not pregnant, not planning conception or not lactating.

A randomized, controlled, parallel intervention trial with two active groups and one blinded control group was carried out for 12 weeks (March to June, 2013). The active food group (n = 21) consumed folate-rich foods (germinated canned faba beans, cookies, orange juice, providing additional 250 μg/d folate); the active folic acid supplement group consumed a supplement (n = 19, providing 500 μg/d folic acid); and the control group (n = 22) received apple juice containing no folate or folic acid) in addition to the freely chosen diet.

Fasted venous blood samples were collected at baseline, two months and three months for quantification of folate in plasma and erythrocytes and of homocysteine in plasma. ;

Study Design

Allocation: Randomized, Endpoint Classification: Bio-availability Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02373033
Study type Interventional
Source Mansoura University
Contact
Status Completed
Phase N/A
Start date March 2013
Completion date June 2013
View Details
See also
  Status Clinical Trial Phase
Completed NCT00789490 - Relative Bioavailability of Iron and Folic Acid in New Test Supplement Phase 1
Enrolling by invitation NCT05389618 - Dietary Challenges in the Population of Nursing Homes' Residents
Completed NCT05453708 - Maternal Risk Factors for Autism Spectrum Disorders: A Case-Control Approach
Completed NCT06174883 - Salt-FA to Increase Folate Levels
Completed NCT03284840 - Adults Nutrition as a Protective or Health-risk Factor
Active, not recruiting NCT04024254 - A Study of Serum Folate Levels in Patients Treated With Olaparib Phase 2/Phase 3
Completed NCT05935631 - Feasibility, Acceptability and Directional Signal Effect on Blood Folate Levels of Iodized Salt Fortified With Folic Acid: Clinical Study N/A
Completed NCT04180800 - Studying the Association Between Folic Acid Deficiency and Social Isolation for Elderly Patients
Completed NCT02674022 - Screening for Metabolic Problems in Mothers of Children With Autism and Typically Developing Children N/A
Completed NCT01297361 - The Association Between Religious Origin and Age, and Vitamin B12 and Folic Acid Plasma Levels in Non Jewish Population in Western Galilee N/A
Recruiting NCT00162409 - Relationship Between Folic Acid and Warfarin Metabolism and Effect N/A
Completed NCT04096521 - Serum Folic Acid Status, Genotyping MTHFR 677C-->T, Plasma Homocysteine, DNA Methylation of IGF2 Gene and Microbiota of the Children: Mother-Children Cohort Study
Completed NCT03978260 - Preoperative Anaemia prevaLence In surgiCal patiEnts
Completed NCT01412580 - In Utero Capacity Formation and Socio-economic Outcomes