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Flushing clinical trials

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NCT ID: NCT03370848 Completed - Dyslipidemias Clinical Trials

Effects of Psyllium on Niacin Tolerability

Start date: March 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether psyllium is effective in reducing flushing due to niacin and also to measure the effect of niacin on cholesterol levels.

NCT ID: NCT03354858 Completed - Infertility Clinical Trials

Follicular Flushing Versus Direct Aspiration

Start date: December 1, 2017
Phase:
Study type: Observational

The purpose of this study is to investigate the impact of follicular flushing on the oocyte recovery rate, oocyte maturity, fertilization rate, and embryo development and utilization as compared to direct aspiration (no flushing) in women undergoing IVF treatment

NCT ID: NCT03149419 Completed - Clinical trials for Endothelial Dysfunction

Hot Flash as a Marker of Cardiovascular Risk in Recent Postmenopause: Effects of Non-hormonal Treatments

Start date: March 1, 2016
Phase: Phase 4
Study type: Interventional

Hot flashes, vasomotor symptoms that affect many postmenopausal women, are associated with cardiovascular disease and endothelial dysfunction. Estrogen therapy, associated or not with progestogens, is the standard treatment for vasomotor symptoms and improves the endothelial function of postmenopausal women with hot flushes, even those with cardiovascular risk factors, such as hypertension. It is not known whether hot flushes are a cause for the development of endothelial dysfunction or are markers of this dysfunction, evidenced by estrogen deficiency, thus representing primitive target organ (vessel) lesion. Paroxetine was approved by the FDA as a non hormonal treatment for menopausal hot flashes. In this double-blind randomized clinical trial, the vascular effects of paroxetine at a dose of 7.5 mg / day, compared to placebo, during 12 weeks are evaluated.

NCT ID: NCT03048318 Completed - Clinical trials for Biliary Complications

Antegrade Arterial and Portal Flushing Versus Portal Flushing Only in LDLT

Start date: October 1, 2015
Phase: Phase 4
Study type: Interventional

Arterial flushing is a standard recommendation in deceased donor liver transplantation but not in living donor liver transplantation due to the risk of arterial intimal injury and short cold ischaemia time. There is recent evidence on benefit of retrograde arterial perfusion using hepatic venous occlusion and its benefits on post transplant cholestasis. However there is no data on antegrade arterial flushing.

NCT ID: NCT02714205 Completed - Clinical trials for Menopausal Hot Flashes

Flushing Reduction Associated With Nitrates

FRAN
Start date: April 24, 2017
Phase: Phase 2
Study type: Interventional

A randomized, double-blinded, placebo-controlled trial of uninterrupted transdermal nitrate therapy in 140 peri- or postmenopausal women who have frequent hot flashes. Women will be randomly assigned to uninterrupted use of transdermal nitrate therapy (participant directed dose-escalation of 0.2 to 0.6 mg/hr) or identical-appearing placebo patches for 12 weeks.

NCT ID: NCT02668185 Completed - Menopausal Flushing Clinical Trials

Neuropeptide Treatment for Hot Flushes During the Menopause

NK3R
Start date: February 1, 2016
Phase: Phase 2
Study type: Interventional

Placebo-controlled, double-blinded, cross-over clinical trial of a new investigational product

NCT ID: NCT02641808 Completed - Infertility Clinical Trials

Does Follicular Flushing Improve the Outcome in Monofollicular IVF Therapy?

Flushing
Start date: August 1, 2016
Phase: Phase 3
Study type: Interventional

Follicular aspiration as well as follicular flushing are standardized techniques and have been practiced in polyfollicular IVF (in vitro fertilization) therapy for years. Monofollicular IVF therapy is a standard technique as well. IVF can be done in natural cycles or with a minimal stimulation with clomifen citrate to achieve a monofollicular response. Our study aims to compare follicular aspiration and follicular flushing in monofollicular stimulation. First the investigators want to answer the question whether flushing is beneficial for the oocyte yield. In case of a positive result the investigators want to establish a recommendation about the optimal number of flushings taking into account the duration of the procedure and the pain during manipulation.

NCT ID: NCT02435069 Completed - Fecal Incontinence Clinical Trials

A Within Subjects Comparison of Two Antegrade Flushing Regimens in Children

Start date: February 9, 2016
Phase: Phase 4
Study type: Interventional

There is a surgical procedure to help children with intractable fecal incontinence gain continence for stool through construction of a tube that connects the abdominal wall to the colon near or through the appendix. This tube allows easy administration of enema solution into the first part of the colon. Putting enema solution through that tube into the colon is called an antegrade continence enema (ACE) and has been shown to work well in helping some but not all children prevent stool accidents. The purpose of this study is to compare a large volume ACE flush using a salt water solution called normal saline with a small volume ACE flush using liquid glycerin. The aims of this study are to: 1) find the most effective dose and flush frequency of each solution needed to prevent stool accidents; 2) compare which solution given at the best dose has the least side effects and 3) to determine if administration of either of the ACE flushing solutions causes electrolyte abnormalities or affects colon health.

NCT ID: NCT02391155 Completed - Infertility Clinical Trials

Follicular Flushing Outcomes in Singles Versus Double Lumen Oocyte Retrieval Needles in Poor Responding Patients

needles(opu)
Start date: January 2015
Phase: N/A
Study type: Interventional

In this study, the investigators aimed to evaluate to the efficacy of the needle type used in follicular flushing in oocyte retrieval in the poorest responders undergoing IVF.

NCT ID: NCT02365350 Completed - Infertility Clinical Trials

Randomized Clinical Trial on Follicular Flushing in IVF

Start date: January 2015
Phase: N/A
Study type: Interventional

The primary objective is to demonstrate superiority of follicle flushing with the STEINER-TAN Needle® as compared to single lumen aspiration in terms of numbers of COCs retrieved.