Fluid Therapy Clinical Trial
Official title:
The Application of Goal-directed Therapy With the Combination of Stroke Volume Variation and Cardiac Index as the Primary Judgment in Non-severe Patients Underwent Gastrointestinal Tumor Surgery
To evaluate the application of fluid-infusion therapy with the combination of stroke volume variation (SVV) and cardiac index (CI) as the primary judgment in non-severe patients underwent resection of gastrointestinal tumor. Fifty patients (ASA Ⅰ-Ⅱ, 26-55 years old, cardiac functional gradingⅠ) scheduled for gastrointestinal tumor surgery were divided into two groups randomly: group C with CI as the primary judgment and group S with the combination of SVV and CI as the primary judgment.
To evaluate the application of fluid-infusion therapy with the combination of stroke volume
variation (SVV) and cardiac index (CI) as the primary judgment in non-severe patients
underwent resection of gastrointestinal tumor.
Methods: Fifty patients (ASA Ⅰ-Ⅱ, 18-55 years old, cardiac functional gradingⅠ) scheduled for
gastrointestinal tumor surgery were divided into two groups randomly: group C with CI as the
primary judgment and group S with the combination of SVV and CI as the primary judgment.
Patients in group C received a therapy with the goal of CI was no less than 2.5L•min-1•m-2
while SVV was less than 12% and CI was no less than 2.5L•min-1•m-2 in group S. Indexes
including MAP、HR、CVP、CI、SVV were recorded at the moment after anaesthetized (T1), when skin
was incised (T2), when the intestina was anastomosed (T3) and after the abdomen was closed
(T4). SaO2、ScvO2 and plasma lactic were determined at T1 and T4 and DO2,VO2 and ERO2 during
the surgery were calculated .The volume of fluid, vasoactive drugs use, the incidence of
adverse cardiovascular events, the convalescence of intestinal peristalsis, hospital stay and
postoperative complications were recorded.
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