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Fluid Loss clinical trials

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NCT ID: NCT06101498 Completed - Acute Kidney Injury Clinical Trials

Peroperative Fluid Management in Major Gynecological Cancer Surgeries

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect of perioperative fluid management on postoperative kidney damage in gynecological cancer surgeries. The main question[s] it aims to answer are: Does fluid management applied with different hemodynamic monitoring methods affect the risk of postoperative AKI? In our clinic, three different fluid management strategies are applied depending on the anesthetist experience. Acute kidney injury will be evaluated according to the postoperative AKIN classification of conventional fluid therapy and targeted fluid therapy with noninvasive or minimally invasive monitoring.

NCT ID: NCT06097923 Completed - Fluid Overload Clinical Trials

Implementation of Fluid Strategies Using Real-time Bioelectrical Analyzer in Surgical Intensive Care Unit (SICU)

Start date: November 30, 2021
Phase: N/A
Study type: Interventional

Precise assessment of postoperative volume status is important to administrate optimal fluid management. Bioelectrical impedance analysis (BIA) which measures the body composition using electric character. Extracellular water (ECW) ratio by BIA represented as the ratio of ECW to total body water (TBW) and is known to reflect the hydration status. Based on this, we aimed to determine whether aggressive fluid control using ECW ratio could improve clinical outcomes through a single blind, randomized controlled trial.

NCT ID: NCT06026475 Completed - Fluid Loss Clinical Trials

Role of Goal Directed Fluid Therapy in Enhanced Recovery After Surgery in Gastro-intestinal Oncosurgeries

GDFT ERAS
Start date: July 13, 2023
Phase: N/A
Study type: Interventional

Enhanced recovery after surgery (ERAS) protocols are multimodal perioperative care pathways designed to achieve early recovery and reducing postoperative morbidity after surgical procedures by maintaining preoperative organ function and reducing the profound stress response following surgery .The key elements of ERAS protocols include preoperative counselling, optimization of nutrition, standardized analgesic and anesthetic regimens , goal directed fluid therapy early mobilization.

NCT ID: NCT05980013 Completed - Blood Loss Clinical Trials

Evaluation of Physiological Variables and Detection of Blood Loss in Healthy Adults With Different Subject Positioning by the CM-1500

Start date: August 28, 2023
Phase: N/A
Study type: Interventional

The study is a prospective, non-randomized, non-blinded, non-significant risk study enrolling up to 60 healthy adult subjects consented to undergo a 1-unit whole blood draw procedure. Subjects will wear the study device (CM-1500) while positioned in either a supine or reclined position during the blood draw and study-required physiological parameters will be captured pre-, during, and post-donation.

NCT ID: NCT05968105 Completed - Postoperative Pain Clinical Trials

Changes in Vessels After Peripheral Block

Start date: August 2, 2023
Phase:
Study type: Observational [Patient Registry]

In patients with fluid deficit, vasoconstriction occurs in peripheral tissues and blood circulation is kept in the central area. It causes arterial vasodilation and hemodynamic variability by increasing the blood volume of the extremity due to the sympathectomy occurring after the block. When the investigators classify patients according to VCI-CI, it will be questioned whether there is a difference between patients' block quality and hemodynamic variability.

NCT ID: NCT05740644 Completed - Fluid Loss Clinical Trials

Clinical Evaluation of the Zynex Monitoring System, Model CM-1600

Start date: February 13, 2023
Phase: N/A
Study type: Interventional

This is a prospective, single-arm, non-randomized, non-controlled single-center study for the evaluation of the Zynex CM-1600 in 20 healthy adults undergoing a manual blood loss of up to 500mL followed by an infusion of 1 liter of normal saline.

NCT ID: NCT05705115 Recruiting - Clinical trials for Hemodynamic Instability

Acetated Ringer´s Solution in Experimental Hypovolemia

Volu-Flow
Start date: March 2, 2024
Phase: Phase 4
Study type: Interventional

Intravenous fluids are often given to increase stroke volume and thereby improve global oxygen delivery. The effect is however often transient, but the effect of a fluid bolus on stroke volume and other hemodynamic variables over time are poorly described. The volume effect of a fluid bolus (effect on blood volume) can be calculated by measuring Haemoglobin. The purpose of this study is to elucidate the hemodynamic effects of a fluid bolus during normovolemia and hypovolemia in healthy volunteers. Study details include: • Study Duration: 2 visits of approximately 2 h duration each + follow-up visit. Visits 1 and 2 are at least 2 days apart. Number of Participants: A maximum of 15 participants will be enrolled to study intervention such that 12 evaluable participants complete the study

NCT ID: NCT05463198 Completed - Fluid Loss Clinical Trials

Evaluation of Physiological Variables and Detection of Blood Loss Using the Zynex Fluid Monitoring System, Model CM-1600

Start date: September 14, 2022
Phase: N/A
Study type: Interventional

The study is a prospective, non-randomized, non-blinded, non-significant risk, multi-center study enrolling up to 500 healthy adult subjects consented to undergo a whole blood donation procedure. The study will involve enrolling subjects that will undergo blood donation wearing the study device (CM-1600 Device) and capture study-required physiological parameters pre-, during, and post-donation.

NCT ID: NCT05278013 Enrolling by invitation - Ascites Clinical Trials

Utility of 2- Octyl Cyanoacrylate (2-OCA)

Start date: January 13, 2022
Phase: N/A
Study type: Interventional

Paracentesis is a commonly performed procedure in the inpatient and outpatient settings for treatment of ascites. The most frequent complication of paracentesis is fluid leak. Risk for this complication can be reduced by following the Z-track technique; however, fluid leaks still occur causing significant morbidity. 2-Octyl cyanoacrylate (2-OCA, Dermabond manufactured by Ethicon Inc) skin adhesive has been used for years for skin closure for wounds from surgical incisions including punctures from minimally invasive surgery and simple trauma lacerations.

NCT ID: NCT05125848 Completed - Dialysis Clinical Trials

Clinical Evaluation of the CM-1500 During Hemodialysis

Start date: November 29, 2021
Phase: N/A
Study type: Interventional

The study is a prospective, single-arm, non-randomized, non-blinded, non-controlled, non-significant risk, single center study enrolling up to 20 subjects consented to undergo a hemodialysis session as a part of their standard prescribed treatment plan. Subjects will consent to undergo non-invasive monitoring with the CM-1500 during three (3) separate sequential hemodialysis sessions.