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Fistula clinical trials

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NCT ID: NCT04507295 Not yet recruiting - Clinical trials for Congenital Diaphragmatic Hernia

Cerebral Blood Flow in Neonates During Thoracoscopic Surgeries

Start date: August 8, 2020
Phase: N/A
Study type: Interventional

the aim of this study is to compare the effect of different modes of mechanical ventilation by using volume-controlled ventilation and pressure-controlled ventilation on cerebral blood flow monitored by cerebral oximetry during thoracoscopic surgeries in neonates.

NCT ID: NCT04502160 Recruiting - Clinical trials for Arteriovenous Fistula

The Northern Ireland Haemodialysis Vascular Access Database

NIVAD
Start date: June 15, 2020
Phase:
Study type: Observational

This is database designed to explore clinical outcomes related to vascular assess in the population of Northern Ireland with CKD Stage 5 and End-stage Renal Failure.

NCT ID: NCT04499144 Completed - Clinical trials for Surgery Site Fistula

A Modified Approach for the Closure of Oral Sinus Communications

Start date: June 26, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to describe a modified surgical approach for the closure of oral sinus communications, using a buccal trapezoidal flap combined with a connective pedicle flap rotated from the palate

NCT ID: NCT04484220 Active, not recruiting - AV Fistula Clinical Trials

Ellipsys Vascular Access System Post Market Surveillance (PS) Study

Start date: April 13, 2021
Phase: N/A
Study type: Interventional

The proposed clinical study is a prospective, non-randomized, multi-center, single-arm, observational, post-market surveillance (PS) study of the Ellipsys Vascular Access System in subjects eligible for arteriovenous (AV) fistula.

NCT ID: NCT04448795 Completed - Pancreas; Fistula Clinical Trials

Impact of Highest Drain Fluid Amylase Levels on Surgical Outcomes and Postoperative Interventions in Patients Undergoing Pancreaticoduodenectomy

Start date: October 1, 2010
Phase:
Study type: Observational

This study investigated the impact of highest drain fluid amylase (DFA) level on postoperative pancreatic fistula (POPF) severity and outcomes of patients undergoing pancreaticoduodenectomy (PD) with POPF. Patient demographics of biochemical POPF and clinically relevant POPF (CR-POPF) were compared. Predictive factors were assessed using binary logistic regression. Receiver operating characteristic curve analysis was performed to determine the optimal cutoff value of highest DFA (beyond 3 days post-PD). The investigators compared length of hospital stay, surgical mortality rates, and need for postoperative interventions by highest DFA level.

NCT ID: NCT04446208 Recruiting - Clinical trials for Post-operative Fistula

Endoscopy for Post-operative Fistula

FISTULENDO
Start date: July 1, 2021
Phase:
Study type: Observational

Endoscopic treatment of early post-operative fistula in patients with underlying esophageal or gastric cancer has now become the standard of care. However, data regarding the yield of this type of treatment is lacking. This study aims to evaluate endoscopic management of this post-operative complication. The main outcome of this prospective observational study conducted in tertiary centers in France is fistula healing defined as the absence of collection on CT scan (with opacification) in a patient on PO diet, 3 months after the end of the endoscopic treatment.

NCT ID: NCT04435249 Not yet recruiting - Clinical trials for Bronchopleural Fistula

ENgineered Tissue Repair of BronchopleUral fiSTula

ENTRUST
Start date: October 2023
Phase: Phase 1/Phase 2
Study type: Interventional

Phase I/II Open-label Study to Assess the Safety and Efficacy of a Novel Tissue Engineered Airway Product, Consisting of Expanded Autologous Bone Marrow (BM) Derived Mesenchymal Stromal Cells (MSC) Seeded on to a Decellularised Allogeneic Patch of an Airway Scaffold in Subjects With Clinically Significant Bronchopleural Fistula.

NCT ID: NCT04418739 Recruiting - Pancreatic Cancer Clinical Trials

Intravenous Human Albumin In Improving Pancreaticoduodenectomy Outcomes

Start date: January 27, 2020
Phase: Phase 2
Study type: Interventional

Pancreaticoduodenectomy (PD), more commonly known as Whipple's surgery is the mainstay treatment for pancreatic head and periampullary cancer. Factors contributing to PD outcomes are broadly categorized to disease-related, patient-related and operative factors. Whereas an inexhaustible list of study exists on looking at reducing PD complication rates with respect to the above-mentioned factors, it was only recently that more attention has been given to the impact of perioperative and intraoperative fluid regimes on PD outcomes. This study takes interest in the impact of intraoperative fluid regimes on PD outcomes. The objective of this investigation is to compare the outcomes with the use of intraoperative intravenous human albumin versus standard intraoperative fluid regimes.

NCT ID: NCT04418323 Recruiting - Clinical trials for Video Assisted Anal Fistula Treatment

Video-assisted Anal Fistula Treatment (VAAFT) Versus Fistula-tract Laser Closure (Filac) Versus Conventional Seton in the Management of Anal Fistula

Start date: June 16, 2020
Phase: N/A
Study type: Interventional

Anal fistula is a chronic inflammatory tract connecting an internal opening in the anal canal with one or more than one external openings in the perianal skin Aim of the work This prospective randomized control trial, we will compare video-assisted anal fistula treatment (Vaaft) and Fistula Laser closure (Filac) and conventional Seton as regards, recurrence rate as a primary outcome. Secondary outcome includes; operative and post-operative data, hospital stay, pain score, healing time, return to work and continence

NCT ID: NCT04416971 Recruiting - Clinical trials for Hemodialysis Complication

Clinical Values of Mature Fistulas in Hemodialysis

Start date: August 20, 2020
Phase:
Study type: Observational

The arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis(HD), and fistula-first is the general recommendation for all HD patients. But in clinical practice in China, quite a few patients start HD before AVF maturation due to various situations. Whether HD initiation with mature AVF will influence the patency and complications is controversial. This study is aim to compare the AVF patency in incident HD patients with mature or immature AVF on HD initiation, and to compare other clinical outcomes, including abandonment without use, infection, and other AVF complications occurrence.