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Fistula clinical trials

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NCT ID: NCT02038504 Completed - Clinical trials for Gastrointestinal Fistula

Investigating the Role of EN in NTIS Among Fistula Patients

EN;NTIS
Start date: January 2013
Phase: N/A
Study type: Observational

The purpose of this study is to investigate whether enteral nutrition are effective in the treatment of nonthyroidal illness syndrome among fistula patients.

NCT ID: NCT02033772 Completed - Clinical trials for Congenital Diaphragmatic Hernia

Prospective Data Collection of Patients < 6 Months of Age Undergoing Thoracoscopic Surgery

Start date: August 2013
Phase: N/A
Study type: Observational

The study is primarily a descriptive study examining the physiological, ventilatory, surgical, and recovery effects of patients ≤ 6 months of age who undergo thoracoscopic surgery and to determine the accuracy of transcutaneous CO2 (TC-CO2) and end-tidal CO2 (ET-CO2) during high frequency oscillatory ventilation (HFOV) and thoracoscopic procedures.

NCT ID: NCT01990833 Completed - Clinical trials for Enterocutaneous Fistulas

Molecular Characteristics of the Persistent Intestinal Fistulae After Glue Application

Start date: January 2012
Phase: N/A
Study type: Observational

For non-healing ulcers, abnormal periods of wound healing processes: inflammation, proliferation and remodelling, are believed to lead to chronic wounds. As a chronic "stalled" wound, investigators hypothesized that these glue-assisted closure (GAC)-failed enterocutaneous fistula (ECF) might have a prolonged inflammatory phase modulated by excessive pro-inflammatory cytokines or proteases. The aim of this study was to analyze the chemicals in ECF wounds in order to determine patients' condition and fitness for GAC.

NCT ID: NCT01954225 Completed - Fistula in Ano Clinical Trials

Role of Udumbara Sutra in the Management of Fistula in Ano a Rare Case Study

Bhagandara
Start date: February 2006
Phase: N/A
Study type: Interventional

The anal fistula is a notorious disease due to its recurrence rate. Bhagandara is varyingly defined as a tear, ulcer or boil at Bhaga (Perianal region) within 2 finger circumference of it, causing painful abscess when opened is called Bhagandara. The Sanskrit word 'Bhagandara' has got two components-Bhaga and Darana. Bhaga means perianal region and Darana means to tear. The ancient Surgeon Sushruta has advocated various types of operations in Sushruta Samhita. He has advocated Kshara Sutra treatment due to probability of recurrence after surgery. Sushruta describes many kind of kshara like Palasa, Kadali. The most remarkable is Udumbara( Ficus Glomerata) among them. The present treatment modality Udumbara Kshara Sutra has been found effective due to its action of proper drainage of pus from the fistula that leads to a proper healing and as adjuvant therapy by avoid recurrence in Fistula in ano. Hypothesis; Present treatment modality Udumber Sutra will found to be useful in tne management of Fistula in ano.

NCT ID: NCT01934075 Completed - Clinical trials for Other Obstetric Trauma OS

Development of Mental Health Treatment for Obstetric Fistula Patients in Tanzania

Start date: September 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a mental health intervention for obstetric fistula patients in Tanzania improves primary outcomes (depression, PTSD and somatic symptoms) and secondary outcomes (coping, perceived stigma, social support, social participation, efficacy to engage with providers, adherence to clinical recommendations and social reintegration).

NCT ID: NCT01928498 Completed - Arteriovenous Graft Clinical Trials

Drug Eluting Balloon for Prevention of Hemodialysis Access Restenosis

DEB
Start date: October 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of paclitaxel-coated balloon catheter to prevent restenosis after PTA (percutaneous transluminal angioplasty) of hemodialysis access (HA) in comparison with the uncoated PTA balloon catheter.

NCT ID: NCT01915927 Completed - Clinical trials for Perianal Crohn's Disease

Stem Cell Fistula Plug in Perianal Crohn's Disease

MSC-AFP
Start date: July 2013
Phase: Phase 1
Study type: Interventional

The investigators propose to study the safety of autologous mesenchymal stromal cell transfer using a biomatrix (the Gore® Bio-A®; Fistula Plug) in a Phase I study using a single dose of 20 million cells. Twenty adult patients (age 18 years or older) with refractory, complicated perianal fistulizing Crohn's disease will be enrolled. Subjects will undergo standard adjuvant therapy including drainage of infection and placement of a draining seton with continuation of pre-existing anti-Crohn's therapy. Six weeks post placement of the draining seton, the seton will be replaced with the MSC loaded Gore® Bio-A® fistula plug as per current clinical practice. The subjects will be subsequently followed for fistula response and closure for 24 months. This is an autologous product derived from the patient and used only for the same patient.

NCT ID: NCT01900691 Completed - Clinical trials for Esophageal Neoplasms

Removal of the Evolution® Esophageal Stent - Fully Covered

CLARITY
Start date: September 2013
Phase: N/A
Study type: Interventional

The CLARITY study is a clinical trial approved by US FDA to study the removal of the Evolution® Esophageal Stent-Fully Covered in malignant and benign indications.

NCT ID: NCT01891149 Completed - Obstetric Fistula Clinical Trials

Ultrasonographic and Hormonal Characteristics of Malawian Women With and Without Obstetric Fistula

Start date: December 2012
Phase: N/A
Study type: Observational

This study is a cross-sectional study of 110 Malawian women to compare the ultrasonographic and hormonal characteristics of women and without obstetric fistula. Hypothesis #1: Women with obstetric fistula have a mean cervical length measurement that is at least 10 mm shorter than the mean cervical length measurement of similar women without obstetric fistula. Hypothesis #2: Evaluation of the hormonal and ultrasonographic characteristics of women with obstetric fistula will allow us to assess the cause of amenorrhea in these women.

NCT ID: NCT01880398 Completed - Fistula in Ano Clinical Trials

Management of Fistula in Ano by Kshar Sutra, Para Surgical Procedure.

Bhagandar
Start date: June 2011
Phase: N/A
Study type: Observational

Background: Fistula in ano is one of the most common diseases of the ano rectal region. Treatment of Fistula in ano has puzzled the medical fraternity due to its complex nature. Commonly prevalent surgical treatment for anal Fistula, that is "Fistulectomy" does not provide successful cure for the disease, post operative complications and recurrences being common. Acharya Sushruta an ancient Indian Surgeon has described in his text ' Sushruta Samhita' about an ancient Ayurvedic technique of medicated thread called Ksharsutra treatment for Bhagandara ( Fistula in ano). Treatment of anal Fistula (Bhagandara)and Nadi-Vrana(Sinus) with Ksharsutra was practiced by Sushruta (1000-600B.C.) . Hypothesis: Aycharya Sushruta advocated Kshar Sutra therapy in Fistula in ano and in various types of Fistula.