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Comparison of Injections of Botulinum Toxin and Topical Nitroglycerin Ointment for the Treatment of Chronic Anal Fissure

Fissure in Ano Clinical Trial

Official title:
A Comparison of Injections of Botulinum Toxin and Topical Nitroglycerin Ointment for the Treatment of Chronic Anal Fissure :A Randomized Controlled Trial

Clinical Trial Summary

Patients will be randomized to receive treatment with either a total of 20 U of botulinum toxin(diluted in saline to a concentration of 50 U per milliliter.

Clinical Trial Description

Lateral internal sphincterotomy, the most common treatment for chronic anal fissure, may cause permanent injury to the anal sphincter, which can lead to fecal incontinence. We compared two nonsurgical treatments that avert the risk of fecal incontinence.treatment with either topical nitroglycerin or botulinum toxin is effective as an alternative to surgery ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05590520
Study type Interventional
Source Pak Emirates Military Hospital
Contact Mubashra Badar
Phone 03145274242
Email mubashrabadar@gmail.com
Status Recruiting
Phase N/A
Start date November 1, 2022
Completion date December 2024
View Details
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