Clinical Trials Logo

First Trimester Abortion clinical trials

View clinical trials related to First Trimester Abortion.

Filter by:
  • None
  • Page 1

NCT ID: NCT05360186 Recruiting - Clinical trials for First Trimester Abortion

New Cross-linked Hyaluronan Gel to Prevent Adhesion After USG-MVA: RCT

Start date: June 14, 2022
Phase: N/A
Study type: Interventional

The objective of this prospective, randomized controlled study was to evaluate the effectiveness of this NCH gel in the prevention of IUA development as assessed by hysteroscopy after USG-MVA, in the treatment for first-trimester miscarriage. - To study the severity and extent of the IUA as assessed by the AFS and ESGE adhesion score in both groups of patients. - To examine the rate of complications or side effects with the NCH gel. - To assess the subsequent menstrual history and reproductive outcome in both groups of patients.

NCT ID: NCT04708808 Recruiting - Pain Clinical Trials

The Effect of Music Therapy Under Ultrasound Guided Manual Vacuum Aspiration

Start date: August 30, 2020
Phase: N/A
Study type: Interventional

Manual vacuum aspiration (MVA) is one of the surgical treatment options for managing early pregnancy loss. When compared to traditional surgical method; MVA is safer, more cost-effective, due to its shorter hospitalisation period and not undergo the risk of general anaesthesia. The MVA procedure is performed under local anaesthesia and analgesics is given prior the procedure. However, majority of patients still complaint significant pain during the procedure. In our previous study, the investigator found women had high anxiety and stress levels when undergo miscarriage and the operation. Pain perception may further be affected by one's psychological state at the time of the procedure. Therefore reducing the patient's anxiety during the USG-MVA may further improve the patient's pain control and overall acceptance of the procedure. Music can act as a distracter and has a calming effect which turn the patient's attention away from negative stimuli. Yet, there has been no RCTs to investigate the beneficial effect of music therapy in pain control or reducing anxiety levels during USG-MVA. The investigator hypothesis the intervention of music therapy to our current pain control will reduce the pain and anxiety levels experienced by our patients during USG-MVA. Thus, there is a need to conduct an RCT to test our hypothesis. The study is conducted in an university affilated hospital for women undergo the USG-MVA procedure. The primary outcome is to evaluate in between group difference in the pain intensity after the USG-guided MVA procedure. The secondary outcome is to evaluate the difference in anxiety level . Case is randomized to music and non music group, Bluetooth headphone are provided during the procedure and case can choose their favourite songs. The outcome are measured by the self rated instrument: Visual analogue scale and the STAI trait anxiety score and the physiological measure salivary alpha amylase (sAA )score. The pain score and the anxiety level is measured pre operatively, immediate after the procedure and 2 hours post operatively. The SPSS-26 will be used for statistics analysis.

NCT ID: NCT04242212 Recruiting - Induced Abortion Clinical Trials

Study of Clinic-based vs. Self-use of a Misoprostol-only Regimen for Induced Abortion

Start date: May 19, 2019
Phase:
Study type: Observational

The goal of the study is to determine whether important clinical outcomes differ among women who access a misoprostol-only medication abortion regimen from a patent medicine vendor when compared with those who access it from a clinic.

NCT ID: NCT03727308 Completed - Induced Abortion Clinical Trials

Study of Clinic-based Versus Self-use of Medical Abortion Pills

MOC
Start date: May 30, 2018
Phase:
Study type: Observational

The goal of the study is to determine whether important clinical outcomes differ among women who access a combined medical abortion regimen from a pharmacy when compared with those who access it from a facility.

NCT ID: NCT03533036 Completed - Virtual Reality Clinical Trials

Virtual Reality Experience in First Trimester D&C

Start date: December 13, 2017
Phase: N/A
Study type: Interventional

Virtual reality (VR) has been used in health care settings to decrease anxiety and pain. This project is a feasibility study to evaluate whether virtual reality can be used in the setting of a first trimester pregnancy termination by D&C and whether the use of virtual reality (VR) headsets can help decrease anxiety for patients during this procedure.

NCT ID: NCT03413774 Completed - Clinical trials for First Trimester Abortion

Unexplained Early Miscarriage : Role and Prevalence of Lower Genital Tract Infections

Start date: October 1, 2014
Phase: N/A
Study type: Observational

The study group included 910 women who attended Fayoum university hospital gynecology outpatient clinic for postabortive evaluation. The control group included 940 women attended outpatient clinic for any other procedure or complaint

NCT ID: NCT03165136 Active, not recruiting - Clinical trials for Recurrent Miscarriage

Hydroxychloroquine for Prevention of Recurrent Miscarriage.

BBQ
Start date: December 4, 2017
Phase: Phase 3
Study type: Interventional

Recurrent miscarriage (RM) defined by >=3 consecutive losses affects 1% of fertile couples. Most women have recurrent early loss with a failure of development before 10 weeks' gestation. Standard investigations fail to reveal any apparent cause in >50% of couples. No study has demonstrated any benefit of any medication in women with Unexplained RM, in the presence or absence of an inherited thrombophilia. Moreover, the benefit of aspirin and/or heparin has not been proved in women with Antiphospholipid (APL) antibody without other clinical manifestations of Antiphospholipid Syndrome. Hydroxychloroquine (HQ) is a molecule whose properties (anti-thrombotic, vascular-protective, immunomodulatory, improved glucose tolerance, lipid-lowering, anti-infectious) could be useful against mechanisms of Unexplained RM. There is no data concerning the benefit of HQ in RM in the presence or absence of antiphospholipid antibodies or any inherited thrombophilia. Administration in (Systemic Lupus erythematosus (SLE) women and for Malaria prevention provides extensive safety data during pregnancy. Oral administration makes possible treatment since the preconception period. For all of that and its low cost, hydroxychloroquine should be evaluated in RM whatever the woman thrombophilic status.

NCT ID: NCT02922504 Completed - Pain Clinical Trials

Impact of Music Intervention on Pain Control In First Trimester Surgical Abortion Under Local Anesthesia

AlgoMusic
Start date: October 2016
Phase: N/A
Study type: Interventional

A surgical abortion under local anesthesia is potentially painful. A protocol using analgetic is systematically used. Also the protocol is relevant , the question of taking care of the pain in a safe manner remains. The use of Music during surgery can have a real effect on pain and anxiety. This study has for goal to evalued the use of music on pain as adjuvant treatement instead of a standard care for an abortion.

NCT ID: NCT02756403 Completed - Clinical trials for First Trimester Abortion

A Randomized Controlled Trial of Three Antibiotic Regimens for First Trimester Abortions

Start date: March 2016
Phase: N/A
Study type: Interventional

This study, a double blinded randomized controlled trial, is being done to compare side effects of commonly used antibiotic regimens prior to same day abortion procedures. In total, 180 pregnant women in their first trimester of pregnancy (5 0/6-13 6/7 weeks gestation) will be randomized to receive one of the three commonly used antibiotics (azithromycin, doxycycline, metronidazole) for same day abortion procedures or placebo prior to their abortion procedure. Approximately, 30-60 mins after study drug administration, the procedure will be performed. A sub-study will be completed on 40 women who consent to endometrial sampling and to have their blood drawn.