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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT06405659
Other study ID # YJLW2019001
Secondary ID
Status Completed
Phase
First received
Last updated
Start date August 6, 2018
Est. completion date September 30, 2023

Study information

Verified date April 2024
Source Affiliated Hospital of Guangdong Medical University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Fever is a common clinical symptom in patients with postoperative scoliosis. However, there are rare reports of immediately fevers occurring following operative procedures.


Description:

Postoperative fever is a common clinical symptom in patients following spinal surgery, with an incidence of 13.2%, and 64.5% of patients with neuromuscular scoliosis were observed to develop postoperative fevers. The most frequently observed cause of fever is surgical trauma, which is associated with inflammatory responses to surgery, and such fevers typically resolve within 2-3 days. This self-limited cause of postoperative fever is non-pathological,4 and the severity and duration of such fevers depend on the duration, scope, and type of surgery, and whether a mesh graft was inserted. The aetiology of immediate postoperative fever for patients following hip prosthesis implantation is unknown, and it is inexpedient to initiate antibiotic treatment or to increase the prophylactic antibiotic dosage. However, there are rare reports of chills and fevers occurring immediately following spinal surgery, to the best of our knowledge, there have been no reports on the mechanism of immediate postoperative fever following spinal surgery. Based on this evidence and on observation, when patients experience postoperative fevers, nearly all surgeons seek to exclude infection as a cause. The case presented in this paper is that of a 15-year-old female with idiopathic scoliosis who underwent posterior idiopathic scoliosis incision and correction for pedicle fixation. The clinical symptoms of interest, including chills, a high fever, an increased heart rate and increased blood pressure, were observed immediately during the course of anaesthesia resuscitation. In this report, risk factors, treatment and prevention are assessed based on the case evidence.


Recruitment information / eligibility

Status Completed
Enrollment 1
Est. completion date September 30, 2023
Est. primary completion date September 30, 2023
Accepts healthy volunteers No
Gender Female
Age group N/A and older
Eligibility Inclusion Criteria: - N/A Exclusion Criteria: - N/A

Study Design


Intervention

Other:
correction for pedicle fixation
The patient was diagnosed with idiopathic scoliosis and underwent a posterior idiopathic scoliosis procedure and correction for pedicle fixation.

Locations

Country Name City State
China The Affiliated Hospital of Guangdong Medical University Zhanjiang Guangdong

Sponsors (1)

Lead Sponsor Collaborator
Affiliated Hospital of Guangdong Medical University

Country where clinical trial is conducted

China, 

References & Publications (39)

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* Note: There are 39 references in allClick here to view all references

Outcome

Type Measure Description Time frame Safety issue
Primary surgical complication Complications related to the surgical procedure up to 3 years, after surgical procedure
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