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Anticholinergic Premedication Induced Fever in Pediatric Ambulatory Anesthesia With Ketamine

Fever Clinical Trial

Official title:
Anticholinergic Premedication Induced Fever in Pediatric Ambulatory Anesthesia With Ketamine

Clinical Trial Summary

Anticholinergic drugs have traditionally been used for their antisialagogue properties. But use of anticholinergic drugs can interfere with thermoregulation via inhibition of the parasympathetically mediated sweat secretion. Sweating inhibition can reduce heat elimination, and children's thermoregulation depend more on sweating than adults and they can become hyperthermic when given these agents.

The investigators evaluated the fever-causing effects of adjunctive anticholinergics in children under general anesthesia using ketamine.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02430272
Study type Interventional
Source Inje University
Contact
Status Completed
Phase N/A
Start date May 2014
Completion date December 2014
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