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Sildenafil Versus Low Molecular Weight Heparin in Fetal Growth Restriction Treatment

Fetal Growth Restriction Clinical Trial

Official title:
Sildenafil Versus Low Molecular Weight Heparin in Fetal Growth Restriction Treatment

Clinical Trial Summary

comparing the effect of using sildenafil citrate and LMWH in treatment of cases of IUGR due to placental insufficiency

Clinical Trial Description

One hundred pregnant women with documented intrauterine growth restriction due to placental insufficiency at 28-35 weeks of gestation will be distributed into two groups:

- Group S: 50 women will receive Sildenafil citrate 25 mg tab 3 times daily.

- Group H: 50 women will receive single dose of LMWH subcutaneous daily.

Both groups will undergo strict fetal surveillance in the form of:

Umbilical artery Doppler (UAD) is the primary surveillance tool in the FGR fetus:

middle cerebral artery (MCA) Doppler, ultrasound for (AC, EFW, and deepest vertical pocket (DVP) for amniotic fluid) and non stress test and Biophysical profile (BPP) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03230162
Study type Interventional
Source Ain Shams University
Contact Radwa R Ali, MD
Phone 01283492979
Email radwaebed@yahoo.com
Status Recruiting
Phase Phase 3
Start date June 1, 2017
Completion date May 1, 2018
View Details
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