Fertility Issues Clinical Trial
Official title:
A Pilot Study on Fertility Conservative Treatment of Atypical Endometrial Hyperplasia in Singapore
The investigators' objective is to determine the regression rate, side effects and acceptability of Mirena compared to megace in the treatment of atypical endometrial hyperplasia among women desiring fertility.
Atypical endometrial hyperplasia is a growing clinical problem that increases the risk of carcinogenesis and negatively impacts fertility. Although oral medical treatment may lead to regression in up to 90% of patients, they are associated with adverse side effects such as weight gain, that negatively affects fertility. To-date, there has been no RCTs evaluating the performance of the Mirena Intrauterine System (IUS) with megestrol acetate (megace) (the most effective and commonly used progestogen) in treating women with atypical hyperplasia who still desire fertility. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06387498 -
Testicular Tissue Cryopreservation (TTC)
|
N/A | |
| Recruiting |
NCT04519593 -
ABSOLUTELY: A Temporary Uterine Blood Supply Occlusion for Laparoscopic Myomectomy in Patients With UTErine LeiomYoma
|
N/A | |
| Recruiting |
NCT05980091 -
Optimal Timing of Euploid Day 6 Blastocyst Transfer in Frozen HRT Cycles, Day 6 or Day 7 of Progesterone Administration.
|
Phase 1 | |
| Recruiting |
NCT06043609 -
Outcome Evaluation After Fertility Preservation
|
||
| Not yet recruiting |
NCT05048771 -
Fertility and Temporality in Pediatric Oncology
|
||
| Completed |
NCT05368194 -
Food Intake and Epigenetic Alteration in the Spermatozoa of Singletons and Twins
|
N/A | |
| Recruiting |
NCT05176535 -
Determination of Vaginal Colonization and the Effect of an Oral Probiotic (PROSALVAG)
|
N/A | |
| Recruiting |
NCT06360471 -
Fertility Preservation and Pregnancy and Offspring Health Outcomes in Female Cancer
|
||
| Recruiting |
NCT05271981 -
Fertility After Uterine Artery Embolization
|
||
| Recruiting |
NCT05815719 -
Continuous Double Ovarian Stimulation.
|
Phase 4 | |
| Recruiting |
NCT06127875 -
Effects of Trying to Conceive Using an Home- or Hospital-based Ovulation Monitoring on Stress
|
||
| Recruiting |
NCT05658848 -
Effect of Collaborative Infertility Counseling on Coping Strategies and Marital Satisfaction
|
N/A | |
| Not yet recruiting |
NCT05385848 -
Autologous Platelet-rich Plasma (PRP) Infusion to Improve Outcomes in Women With Ovarian Insufficiency: a Pilot Study
|
N/A | |
| Completed |
NCT04396210 -
Patients Perspectives on Discontinuation of Their Fertility Treatment Due to the COVID-19 Pandemic
|
||
| Completed |
NCT05134090 -
Percutaneous Laparoscopy for Ovarian Tissue Cryopreservation.
|
||
| Completed |
NCT05905289 -
Survival and Reproductive Outcomes of Malignant Ovarian Germ Cell Tumors
|
||
| Recruiting |
NCT05316467 -
Weight Management Plus Megestrol Acetate in Early-stage Endometrioid Carcinoma
|
Phase 2/Phase 3 | |
| Completed |
NCT04600869 -
Effects of Naturalistic Decision-Making Model-based Oncofertility Care Education
|
N/A | |
| Withdrawn |
NCT04683237 -
Liraglutide Plus Megestrol Acetate in Endometrial Atypical Hyperplasia
|
Phase 2/Phase 3 | |
| Not yet recruiting |
NCT06179420 -
The Effectiveness of Advanced Decision Support Tool (OPT-IVF) for IVF Treatment
|