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99mTc-DARPinG3-based HER2 Expression Molecular Imaging in HER2-positive Breast Cancer During Chemo+Targeted Therapy

HER2-positive Breast Cancer Clinical Trial

Official title:
SPECT Imaging of Human Epidermal Growth Factor Receptor 2 (HER2) Using 99mTc-DARPinG3 in HER2-positive Breast Cancer Patients in Dynamic of Chemo+Targeted Therapy

Clinical Trial Summary

An open-label, single center study with 99mTc-DARPinG3 SPECT and biopsies of primary tumour in HER2-positive Breast Cancer in dynamic of chemo+targeted therapy, where the primary endpoint of the study is to find out the correlation between the HER2 expression measured by 99mTc-DARPin G3 SPECT and standard histopathology from primary tumor in dynamic of chemo+targeted therapy.

Clinical Trial Description

none Methodology: Open-label, exploratory, single center study. The subjects will receive a single injection of the labelled tracer. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05412459
Study type Observational
Source Tomsk National Research Medical Center of the Russian Academy of Sciences
Contact
Status Completed
Phase
Start date May 1, 2022
Completion date January 31, 2023
View Details
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