Febrile Illness Acute Clinical Trial
Official title:
Treatment of Febrile Infectious Disease Among Children in Hadera District Given the Final Diagnosis. Descriptive Study
Study goal - to describe pediatric patients with febrile disease that administered to the
emergency department (ED) of hillel-yaffe hospital, according to arrival diagnosis, ED
diagnosis, given therapy, and therapy concordance with the guidelines and final diagnosis.
This research will describe cases that arrived to the hospital with acute febrile disease
(up to seven days of fever), the antibiotic treatment given in the community according to
the anamnesis and the community physician letter, therapy concordance with the guidelines,
the ED diagnosis and changes in therapy, and final diagnosis according to extended
microbiological examinations and panel of infectious disease specialists.
Status | Not yet recruiting |
Enrollment | 500 |
Est. completion date | December 2015 |
Est. primary completion date | December 2015 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | N/A to 18 Years |
Eligibility |
Inclusion Criteria: 1. Children aged 7 days to 18 years. 2. Body temperature that is higher than 37.5°C (Rectal or Oral). 3. Informed consent obtained from parents. Exclusion Criteria: 1. Children with fever that is longer than 7 days. 2. Children diagnosed with immunodeficiency. 3. Children that receive chemotherapy. 4. Children treated with high dose steroids. |
Observational Model: Cohort, Time Perspective: Retrospective
Country | Name | City | State |
---|---|---|---|
Israel | Hillel Yaffe MC, | Hadera |
Lead Sponsor | Collaborator |
---|---|
Hillel Yaffe Medical Center |
Israel,
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Dagan R, Leibovitz E, Greenberg D, Yagupsky P, Fliss DM, Leiberman A. Dynamics of pneumococcal nasopharyngeal colonization during the first days of antibiotic treatment in pediatric patients. Pediatr Infect Dis J. 1998 Oct;17(10):880-5. — View Citation
Ladhani S, Gransden W. Increasing antibiotic resistance among urinary tract isolates. Arch Dis Child. 2003 May;88(5):444-5. — View Citation
Scheifele D, Halperin S, Pelletier L, Talbot J. Invasive pneumococcal infections in Canadian children, 1991-1998: implications for new vaccination strategies. Canadian Paediatric Society/Laboratory Centre for Disease Control Immunization Monitoring Program, Active (IMPACT). Clin Infect Dis. 2000 Jul;31(1):58-64. Epub 2000 Jul 24. Erratum in: Clin Infect Dis 2000 Sep;31(3):850. — View Citation
Seppälä H, Nissinen A, Järvinen H, Huovinen S, Henriksson T, Herva E, Holm SE, Jahkola M, Katila ML, Klaukka T, et al. Resistance to erythromycin in group A streptococci. N Engl J Med. 1992 Jan 30;326(5):292-7. — View Citation
Whitney CG, Farley MM, Hadler J, Harrison LH, Lexau C, Reingold A, Lefkowitz L, Cieslak PR, Cetron M, Zell ER, Jorgensen JH, Schuchat A; Active Bacterial Core Surveillance Program of the Emerging Infections Program Network. Increasing prevalence of multidrug-resistant Streptococcus pneumoniae in the United States. N Engl J Med. 2000 Dec 28;343(26):1917-24. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | pathogen map of febrile illness | 1 year | No | |
Secondary | antibiotic over use map | 1 year | No |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
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The Effects of Amino Acid Supplement During Acute Inflammation.
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N/A |