Fatigability Post Stroke Clinical Trial
Official title:
Evaluation of the Value of Cerebral Perfusion Scintigraphy in the Study of Post-stroke Fatigability
| NCT number | NCT03543280 |
| Other study ID # | 6787 |
| Secondary ID | |
| Status | Recruiting |
| Phase | |
| First received | |
| Last updated | |
| Start date | February 23, 2018 |
| Est. completion date | February 2019 |
At present there is no consensus for post-stroke imaging except for the realization of early
cerebral CT at 24 hours post-thrombolysis. The use of cerebral perfusion scintigraphy would
predict the course of a stroke. Indeed, it has been shown that a good perfusion is linked to
a good evolution of the neurological deficit. This test is used routinely to evaluate
cerebral perfusion in patients with stroke. This technique was also used to study the
mechanisms of post-stroke aphasia and to highlight neuronal disconnections after stroke, a
reflection of the functioning of neural networks.
Neuropsychological tests are almost always done at 3 months. Fatigue is studied: PSF scale at
3 months, 6 months and 2 years. Research needs to be continued in this area because the
pathophysiology remains unknown and the symptoms are disabling for patients. Using cerebral
perfusion imaging would bring elements of understanding of this mechanism and ultimately
improve the management of patients.
| Status | Recruiting |
| Enrollment | 32 |
| Est. completion date | February 2019 |
| Est. primary completion date | February 2019 |
| Accepts healthy volunteers | |
| Gender | All |
| Age group | 18 Years to 60 Years |
| Eligibility |
Inclusion Criteria: - Patients: 18 to 60 years old at the initial diagnosis - Admission for transient ischemic attack, stroke, dissection, TVC - RANKIN less than or equal to 2 - Neuropsychological tests at +3 months: MoCA> 26 (to eliminate cognitive deteriorations too important for the good realization of the battery) - Absence of psychiatric history - Absence of psychotropic medication - No history of stroke - No complaint of pre-stroke fatigue - Having signed the consent form Exclusion Criteria: - Impossibility of giving the subject or his family enlightened information (subject in emergency situation, difficulties in understanding the subject, etc.) - Subject under the protection of justice - Subject under guardianship or curatorship - Refusal of the patient to participate in the study |
| Country | Name | City | State |
|---|---|---|---|
| France | Service de Biophysique et de Médecine Nucléaire | Strasbourg |
| Lead Sponsor | Collaborator |
|---|---|
| University Hospital, Strasbourg, France |
France,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Evaluate fatigue symptoms in stroke patients | After the period following a stroke: 1 month |