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Facies clinical trials

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NCT ID: NCT03284125 Completed - Clinical trials for Peripheral Facial Paralysis

Lengthening Temporalis Myoplasty and Improvement of Primary Swallowing Disorders in Facial Paralysis

MATPF
Start date: September 2, 2017
Phase:
Study type: Observational

The facial paralysis is a frequent disease causing important functionals swallowing dysfunctions. The purpose of our study was to evaluate the improvement of the swallowing disorders after surgery by lengthening temporalis myoplasty (LTM) in the facial paralysis. This prospective study has realised on the following of patients affected by facial paralysis treated by LTM. Self-administered questionnaires and clinics tests had realized to analyze three components oh the oral phase of the swallowing ( drooling, mastication and handicap). The evaluations was realized before the surgery and at 3 and 6 months after .

NCT ID: NCT03282721 Completed - Clinical trials for Transverse Facial Cleft

Transverse Facial Cleft Repair Using Precise Location of Commissure

Start date: January 1, 2012
Phase:
Study type: Observational

To compare the effect of redesigned transverse facial cleft treatment and traditional transverse facial cleft treatment.

NCT ID: NCT03258164 Completed - Clinical trials for Breast Hypoplasia and Facial Ageing

Cosmetic Fat Transplantation Using Expanded ASC Enriched Fat Grafts

Start date: March 22, 2017
Phase: Phase 3
Study type: Interventional

The purpose of the present study is to examine whether enrichment of a fat graft with autologous ex vivo expanded ASC injected into the breast tissue or face, both for cosmetic use, will significantly improve the results of conventional lipofilling and synthetic facial fillers, thereby being able to offer a safer, more natural and long-lasting alternative to current artificial solutions for cosmetic patients.

NCT ID: NCT03142451 Completed - Clinical trials for Facial Papulopustular Rosacea

A Study (Study 1) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea

Start date: June 2, 2017
Phase: Phase 3
Study type: Interventional

The primary objectives of this study are to determine the efficacy and safety of FMX103 1.5% minocycline foam applied topically once daily for 12 weeks in the treatment of rosacea.

NCT ID: NCT03139903 Completed - Seckel Syndrome Clinical Trials

The Primordial Dwarfisms: Diagnosis, Identification of the Molecular Basis of Seckel Syndrome and Microcephalic Osteodysplastic Primordial Dwarfism Type II

NANPIM
Start date: July 28, 2010
Phase: N/A
Study type: Observational

The purpose of this study si to define morphological and epidemiological parameters and identify new symptoms in French patients with Seckel syndrome (SCKL) or microcephalic osteodysplastic primordial dwarfism type II (MOPDII).

NCT ID: NCT03115203 Recruiting - Facial Paralysis Clinical Trials

Morphometric Study of the Muscles of the Skin in MRI 3 Tesla in Patients With Facial Paralysis.

SIMOVI IRM 2
Start date: August 8, 2016
Phase: N/A
Study type: Interventional

The problem posed is the possibility of objectively assessing facial muscle mobility. Today, in patients with facial paralysis, the assessment of the deficit is carried out using a subjective scale such as the House Brackman [1] or EMG scale of the facial nerve but does not distinguish each muscle individually . Objective measurements of skin muscles such as thickness and volume, in preoperative assessment of a facial paralysis rehabilitation surgery, would be useful in order to choose the most appropriate surgical technique. Indeed, too much amyotrophy will contraindicate hypoglosso-facial anastomosis (VII-XII) and it will be preferable to propose a temporal elongation myoplasty or a reinfused free muscle flap. Similarly, it would be useful to be able to objectively evaluate the recovery of muscle function after facial allo-transplantation. Although electromyography has been developed since the work of Duchenne de Boulogne, little research has been carried out on the development of noninvasive methods to objectively characterize in vivo skin muscles (variation, position, orientation, morphometry). The main morphometric data of the skin muscles come from anatomical dissections. Imaging of the skin muscles has not been specifically developed. Some studies have been carried out to visualize these muscles in MRI 1.5 Tesla in pathologies such as myasthenia gravis, facial paralysis, and labio-alveolo-palatine clefts for example. The originality of the project is to develop a method allowing to establish a quantitative correlation between the movements of the face and the muscular changes. This correlation will be achieved by associating muscular morphological data derived from MRI acquisitions and cutaneous deformations resulting from clinical examinations. This non-invasive approach should make it possible to establish objective and reproducible indicators in patients with facial paralysis sequelae.

NCT ID: NCT03059420 Recruiting - Facial Palsy Clinical Trials

Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies

Start date: February 1, 2004
Phase:
Study type: Observational

The purpose of this study is to identify genes associated with impaired development and function of the cranial nerves and brainstem, which may result in misalignment of the eyes (strabismus) and related conditions.

NCT ID: NCT03050749 Completed - Facial Lipoatrophy Clinical Trials

Safety and Performance of Princess® VOLUME for the Treatment of Facial Lipoatrophy, Asymmetry or Scars

FLASH2
Start date: November 20, 2016
Phase: N/A
Study type: Interventional

In this study, eligible patients with the medical indications (facial lipoatrophy, morphological asymmetry of the face, or debilitating scars) will be treated with Princess® VOLUME, and then will return for follow-up assessments 2, 4, 24, and 36 weeks after the treatment. A touch-up treatment may be done 2 weeks after the treatment if deemed appropriate by the Investigator.

NCT ID: NCT03050723 Completed - Facial Lipoatrophy Clinical Trials

Safety and Performance of Princess® FILLER for the Treatment of Facial Lipoatrophy, Asymmetry or Scars

FLASH 1
Start date: November 20, 2016
Phase: N/A
Study type: Interventional

In this study, eligible patients with the medical indications (facial lipoatrophy, morphological asymmetry of the face, or debilitating scars) will be treated with Princess® FILLER, and then will return for follow-up assessments 2, 4 and 24 weeks after the treatment. A touch-up treatment may be done 2 weeks after the treatment.

NCT ID: NCT03048383 Completed - Facial Asymmetry Clinical Trials

Comparison of Three Botulinum Neuromodulators for Management of Facial Synkinesis

Start date: July 2012
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the effectiveness of three commercially available botulinum toxin neuromodulators in the treatment of facial synkinesis using patient reported outcome measures.