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Facies clinical trials

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NCT ID: NCT06321770 Completed - Facial Wrinkles Clinical Trials

Oral Supplementation With Active Collagen Peptides and Skin Health Improvement

Start date: March 15, 2023
Phase: N/A
Study type: Interventional

The present study aims to investigate the efficacy of daily supplementation with COLLinstant® LMW over a 6-week period in improving visible signs of aging. This in-cludes assessing its impact on skin wrinkle reduction, as well as its potential to en-hance skin elasticity and moisturization. COLLinstant® LMW was administered orally in a single-center, randomized, double-blind, placebo-controlled clinical trial. A sec-ondary objective involves comparing skin improvement, product satisfaction, and monitoring adverse events among middle-aged female volunteers.

NCT ID: NCT06227260 Completed - Clinical trials for Facial Mask From Snake Fruit

Body Massage Oil, Facial Mask, and Ready-to-drink Jelly From Snake Fruit

Start date: March 20, 2023
Phase: Phase 2
Study type: Interventional

This study consisted of three sub-studies including 1) development and evaluation of body massage oil from Snake fruit on skin moisture, elasticity, oiliness, and melanin in healthy participants 2) development and evaluation of facial mask from Snake fruit on skin moisture, elasticity, oiliness, and melanin in healthy participants and 3) development and evaluation of ready-to-drink jelly from Snake fruit on controlling blood glucose and endurance time in healthy participants.

NCT ID: NCT05922956 Completed - Social Cognition Clinical Trials

Facial Emotion Recognition in Patients With Euthymic Bipolar Disorder I and II

REF-BIP
Start date: April 1, 2020
Phase: N/A
Study type: Interventional

The facial emotion recognition is a basic social skill for successful social interactions. Several meta-analyses and recent studies found impairments of the perception of facial emotions in patients with euthymic bipolar disorder. Few studies compared recognition of facial emotions impairments during euthymia in patients with bipolar disorder type 1 and 2. These studies included low population samples (N<60). There were discrepancies in results of these studies. Szanto suggested that facial emotion recognition impairments were correlated with suicidal risk and social isolation. These impairments should be taking into account regarding psycho-social treatments in patients with bipolar disorder. This study aims to evaluate facial emotion recognition in patients with bipolar I and II disorders compared to healthy controls, using the facial emotion recognition test (TREF). The objective of the present study is to compare TREF scores in a group of patients with bipolar 1, a group of patients with bipolar 2 disorder and a group with healthy controls. In addition, the investigators will investigate the relationships between TREF scores and levels of self-esteem and mental well-being.

NCT ID: NCT05897918 Completed - Clinical trials for Patient With Facial Erythema

Tranexamic Acid in Treatment of Facial Erythema

Start date: August 1, 2020
Phase: N/A
Study type: Interventional

Our aim is to evaluate the efficacy of 10% topical tranexamic acid with microneedling in treatment of facial erythema

NCT ID: NCT05830747 Completed - Clinical trials for Tooth Extraction Status Nos

Effect of Pre-emptive Dose of Prednisone Versus Placebo in Impacted Third Molar Surgery

Start date: February 1, 2022
Phase: Phase 4
Study type: Interventional

The present study proposes to compare the effect of a single preoperative dose of prednisone versus placebo in terms of facial swelling, trismus and pain after surgical removal of the mandibular third molar (M3M) in a split-mouth randomized controlled clinical trial.

NCT ID: NCT05798650 Completed - Facial Satisfaction Clinical Trials

the Effect of Viewing Idealized Smile Images Versus Nature Images Via Social Media on Immediate Facial Satisfaction in Young Adults: a Randomized Controlled Trial.

Start date: January 5, 2023
Phase: Phase 1
Study type: Interventional

The study was conducted to investigate the effect of social networking site on facial and smile dissatisfaction, face related discrepancy, and whether these effects differ from the use of appearance-neutral Instagram images.

NCT ID: NCT05647551 Completed - Facial Lines Clinical Trials

A Study to Evaluate Satisfaction in Adult Participants With the Aesthetics of the Periorbital Area After JUVÉDERM® Fillers and BOTOX®/VISTABEL® Injections

Start date: January 5, 2023
Phase: Phase 4
Study type: Interventional

Different studies have shown the negative effects of aging around the area of the eyes. Signs of aging may contribute to erroneously projected emotions (e.g., anger, tiredness, or sadness) that do not reflect the individual's true feelings affecting interpersonal relationships. Minimally invasive aesthetic treatments with botulinum toxin and hyaluronic acid (HA) fillers are used to treat wrinkles and volume deficiencies associated with the appearance of most of the signs of aging. This Phase 4 post-marketing study is an open-label study in which all subjects will receive active study treatment. The purpose of this study is to evaluate the subject's satisfaction after the treatment of JUVÉDERM® fillers and BOTOX®/VISTABEL® on the upper and/or mid face, which includes areas around the eyes, under the eyes, eyebrows, the temple, and the cheek. This study will enroll approximately 80 healthy male and female subjects ages 40 to 65 across 10 sites in Australia, Belgium, and United Kingdom. Each subject will be in the study for approximately 90 days. The initial treatment of the JUVÉDERM fillers (Juvéderm VOLBELLA with lidocaine, Juvéderm VOLIFT with lidocaine, and/ or Juvéderm VOLUMA with lidocaine) will be given on Visit 2, and if needed, a touch-up treatment will be given. On Visit 4, the Juvéderm VOLBELLA with lidocaine filler, may be given, followed by a touch-up treatment, if needed. On Visit 6, subjects will receive study drug BOTOX/VISTABEL. All subjects will return for the study exit visit on Day 90. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, checking for side effects, and completing questionnaires.

NCT ID: NCT05585333 Completed - Facial Paralysis Clinical Trials

Photobiomodulation Therapy Treatment on Facial Paralysis

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Objective: Facial paralysis can be caused by a variety of etiological factors, complete palsy continues for two months, the chance of full recovery is reduced to zero. The aim of this study was to evaluate the effectiveness of photobiomodulation therapy (PBMT) in the in patients undergoing facial paralysis over 8 weeks. Methods: This study was an open-label, not concurrent control study including 54 patients that underwent facial paralysis over 8 weeks. Patients were assigned to the PBMT group and control group, with 27 patients in each group. Laser treatments were applied 3 days a week after recruited. PBMT was delivered using a class IV Multi-wave Locked System that combines with a simultaneous 808 nm continuous emission and 905 nm pulse emission and the maximum peak power was 25 W. Clinical outcome measure comprised the House-Brackmann grading system, Facial Clinimetric Evaluation Scale (FaCE), Sunnybrook facial grading scale (SBFG), and electrophysiological testing, including Electroneuronography (ENoG), Electromyography (EMG) and Blink Reflex. All the measurements were collected at the first day and at the end of study. All reported P values were two-sided and were declared statistically significant when less than 0.05.

NCT ID: NCT05504473 Completed - Facial Nerve Palsy Clinical Trials

Blink Restoration in Patients With Facial Nerve Palsy

NEURO-BLINK
Start date: March 31, 2022
Phase: N/A
Study type: Interventional

This study is a non-blinded single armed pilot study aiming to apply a newly created medical device in patients with seventh nerve palsy suffering from lagophthalmus in order to determine the best way for neuromuscular stimulation of the orbicularis oculi muscle and facial nerve in order to enable eyelid closure (blink). Initially, a tailored external neurostimulation prototype will be created in collaboration with the ETH for patients with facial nerve palsy and lagophthalmos. Aim of this study is to create an efficient, safe and comfortable medical device that can achieve an effective blinking through external electrical neuromuscular stimulation of the orbicularis oculi in patients with facial palsy and lagophthalmos. Such a device can become an essential part of facial palsy treatment.

NCT ID: NCT05476406 Completed - Skin Hydration Clinical Trials

Clinical Study to Evaluate the Impact of aKwa Skincare System on Skin Health

Start date: April 11, 2019
Phase: N/A
Study type: Interventional

The purpose of the study was to evaluate the effectiveness of the äKwä 6-step skincare system by measuring skin moisture level, fine lines and wrinkles, porphyrin count, red spots, and red vasculature counts over a 30-day period.