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Eye Health clinical trials

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NCT ID: NCT05533658 Completed - Cognitive Function Clinical Trials

The Effects of VisionPure™ on Indices of Vision Health and Cognitive Function

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

VisionPure™ is a softgel dietary supplement containing fish oil, lutein, zeaxanthin, and vitamin D. The intent of the VisionPure product is to assist in maintaining eye and cognitive health while helping to provide protection against blue throughout the day. In this pilot trial, approximately 16 participants will be recruited and randomly assigned to experimental and placebo conditions. Participants will consume 1 serving (2 softgels) per day of their respective study condition for 60 days. Prior to and following the 60 day supplementation period, participants will undergo a series of optometry and cognitive examinations to quantify eye health and cognitive function outcomes.

NCT ID: NCT05064865 Active, not recruiting - Clinical trials for Age-related Macular Degeneration

Impact of Regular Consumption of Grapes on Eye Health in Singapore Older Adults

Start date: January 28, 2022
Phase: N/A
Study type: Interventional

Aging epidemics in Singapore are rapidly increasing and Age-related macular degeneration (AMD) prevalence is significantly associated with older age. This study aims to understand the effect of consuming freeze-dried table grape powder on AMD in an older population.

NCT ID: NCT00718653 Completed - Eye Health Clinical Trials

Effects of Antioxidants on Human Macular Pigments

Start date: September 2004
Phase: N/A
Study type: Interventional

Age-related macular degeneration (AMD) is the leading cause of blindness in the United States. Low dietary intake or low blood levels of lutein and zeaxanthin, which are the only pigments found in the macular region of the human retina, has been associated with an increased risk for AMD. We have reported that the dietary supplementation of lutein and zeaxanthin can increase the macular pigments (MP) of the eye. MP effectively absorbs blue light as well as quenches reactive oxygen species (ROS). Green tea polyphenols are also effective scavenger of ROS in vitro. Our goal is to elucidate how to effectively increase MP by physiologic levels of antioxidant supplementation. We hypothesize that lutein and tea polyphenols protect the macula of the eye by increasing MP carotenoids effectively through an antioxidant mechanism.