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The Flashing Light-Induced Pupil Response (FLIPR) Glaucoma Study — FLIPR  

Glaucoma, Open-Angle Clinical Trial

Official title:
The Flashing Light-Induced Pupil Response (FLIPR) Glaucoma Study

Clinical Trial Summary

This study is designed to investigate whether the pupil response to slowly flashing colored lights is significantly altered in patients with glaucoma, as compared to a control group of subjects without glaucoma.

Clinical Trial Description

The pupils inside the eyes constrict in response to light stimulation. Different classes of cells within the human retina initiate this response. Recent research suggests that one of the ganglion cell types involved in this pupil response is affected by glaucoma. By measuring pupil responses to different colored lights, the function of this class of cells can be evaluated quickly, and without touching the eye. An advantage of pupil testing strategies is that they do not require subjective feedback from the subject about what they can see, as is required for standard visual field tests that are used in the clinic.

The main aim of this study is to measure and compare the pupil constriction that occurs in response to flickering red and blue lights in patients with glaucoma versus matched control patients without glaucoma. In addition, the subjects will be asked questions about their quality of life and it will be determined whether issues related to quality of life correlate to alterations in the pupil responses. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01857440
Study type Observational
Source Ohio State University
Contact
Status Completed
Phase N/A
Start date May 2013
Completion date December 2015
View Details
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