Glaucoma, Open-Angle Clinical Trial
— FLIPROfficial title:
The Flashing Light-Induced Pupil Response (FLIPR) Glaucoma Study
Verified date | September 2017 |
Source | Ohio State University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
This study is designed to investigate whether the pupil response to slowly flashing colored lights is significantly altered in patients with glaucoma, as compared to a control group of subjects without glaucoma.
Status | Completed |
Enrollment | 32 |
Est. completion date | December 2015 |
Est. primary completion date | December 2014 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - 18+ years old - Diagnosed with glaucoma of known severity (cases only) - Have a refractive error between +4.00 and -8.00 sphere power, and no more than 3.00 diopters of astigmatism - Best corrected visual acuity of 20/40 or better in each eye - Have open anterior chamber angles Exclusion Criteria: - Diagnosis of glaucoma of a type other than Primary Open Angle (cases only) - History of having surgery or taking medications known to profoundly affect pupillary function or shape - Visual Field defect (controls only) - History of traumatic brain injury requiring hospitalization - Pregnancy - History of optic nerve disease other than glaucoma - History of retinopathy - History of unreactive pupils - Presence of significant cataract |
Country | Name | City | State |
---|---|---|---|
United States | Havener Eye Institute | Columbus | Ohio |
United States | OSU College of Optometry | Columbus | Ohio |
Lead Sponsor | Collaborator |
---|---|
Ohio State University |
United States,
Shorter P, Eren D, Jain SG, Hartwick ATE. 2014. The flashing light-induced pupil response (FLIPR) glaucoma study. Invest. Ophthalmol. & Vis. Sci. 55: E-abstract 5608.
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Pupil Response | Using fourier analysis, the pupil fluctuation evoked by blue and red flickering lights will be measured in glaucoma patients and compared to matched controls. | Single Visit: One Day | |
Secondary | Quality of Life Survey | Subjects will fill out a questionnaire with questions that assess quality of life issues, and the results will be correlated to the pupil response data. | Single Visit: One Day |
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