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Eye Diseases clinical trials

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NCT ID: NCT06162585 Enrolling by invitation - Clinical trials for Retinitis Pigmentosa

Non-Interventional Long Term Follow-up Study of Participants Previously Enrolled in the RESTORE Study

REMAIN
Start date: December 8, 2023
Phase:
Study type: Observational

This study will be conducted following Good Clinical Practice (GCP) and International Conference on Harmonization (ICH) guidelines. Eligible subjects will be consented to return for scheduled study visits for this study following their completion in study NTXMCO-002 (RESTORE). They will not receive a second treatment with MCO-010 (or a repeated sham injection) in this study

NCT ID: NCT05944757 Enrolling by invitation - PRP Clinical Trials

Compare of PRP Autologous Serum and Autologous Serum by Intrastromal Injection in Different Eye Disease Conditions

prp
Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Platelet-rich plasma (PRP) is an autologous blood product rich in proteins and growth factors. Its application has been the subject of many studies in the field of ophthalmology to stimulate tissue healing and regeneration. Due to its anatomical features (lack of blood vessels), the cornea is among the most susceptible to damage structures of the eye. Therefore, the study of the impact of various regenerative therapies (autologous blood products, serums, ) on corneal lesions is important not only scientifically, but also practically for ophthalmologist. Numerous reports described the healing effect of PRP on corneal lesions.

NCT ID: NCT05758753 Enrolling by invitation - Dry Eye Disease Clinical Trials

QST for Corneal Nerve Function

Start date: May 16, 2023
Phase: N/A
Study type: Interventional

This study is designed to learn more about the impact different types of stimuli, such as heat, cold and vibration, can have on ocular pain response. This is called quantitative sensory testing (QST). Most procedures being performed in this study, except the QST, are standard of care which means they are performed during the participant's routine eye examination.

NCT ID: NCT05241626 Enrolling by invitation - Thyroid Eye Disease Clinical Trials

AS-OCT of the Cornea in Thyroid Diseases

Start date: May 11, 2021
Phase:
Study type: Observational

use the anterior segment optical coherence tomography (AS-OCT) to evaluate the tear meniscus parameters, total corneal thickness (CT), and epithelial thickness in active and inactive thyroid eye diseases (TED) patients and compare them with age-matched controls.

NCT ID: NCT04884217 Enrolling by invitation - Dry Eye Syndrome Clinical Trials

Treatment of Dry Eye Disease Using Pro-ocularâ„¢ - A Proof of Concept, Safety, and Efficacy Study

Start date: May 20, 2021
Phase: Phase 2
Study type: Interventional

To evaluate the safety and efficacy of 1% Pro-ocular topical gel administered twice daily for 12 weeks in treatment of Dry Eye Disease

NCT ID: NCT04458012 Enrolling by invitation - Dry Eye Clinical Trials

Epidemiological Study of Dry Eye Disease in Stavanger: Dry Eye Disease in Patients Treated With Intravitreal Injections

EPISTA1
Start date: June 25, 2020
Phase:
Study type: Observational

To investigate prevalence of dry eye disease in Norwegian patients with age-related macular degeneration receiving intravitreal injections, as well as to reveal possible risk factors of DED in this population.

NCT ID: NCT04421300 Enrolling by invitation - Dry Eye Clinical Trials

A Randomized Study of Smile Exercise for Dry Eye

Start date: July 2, 2020
Phase: N/A
Study type: Interventional

The objective of the study is to evaluate the effectiveness of laughter therapy in relieving the symptoms of dry eye disease.

NCT ID: NCT03665090 Enrolling by invitation - Clinical trials for Diabetic Retinopathy Visually Threatening

Shanghai Cohort Study of Diabetic Eye Disease

SCODE
Start date: January 1, 2016
Phase:
Study type: Observational

To describe the design, methodology and baseline characteristics of the Shanghai Cohort study of Diabetic Eye disease (SCODE) study, a community-based study to determine the prevalence and impact of diabetic eye disease, especially diabetic retinopathy (DR), in adults with diabetes living in Shanghai.

NCT ID: NCT03076697 Enrolling by invitation - Diabetes Mellitus Clinical Trials

Smartphone Screening for Eye Diseases

Start date: April 16, 2015
Phase:
Study type: Observational

To validate new screening instruments for eye disease, increase eye care access in underserved communities, and provide a scientifically implemented method to set up programs for eye disease screening.

NCT ID: NCT01396967 Enrolling by invitation - Cataract Clinical Trials

Trying a New Device for Performing Capsulorhexis in Cataract Surgery Surgery

Start date: July 2011
Phase: Phase 1
Study type: Interventional

During cataract operations a capsulorhexis is being performed. This is done in order to enable the removal of lens material while keeping the capsule intact in order to put inside the lens capsule an artificial intra ocular lens. The capsulorhexis must be round and with regular edge and no tears. While performing a cataract surgery we use phako emulsification machine that sends an ultrasonic wave that creaks the lens nucleus and at the same time irrigates the anterior chamber of the eye and sucks the fluid and the lens material of the creaked lens. The round shape and the regularity of the capsulorhexis are a must in these surgeries since the lens capsule must stay intact and stable in order to enable the phacoemulsification and the implant of the artificial lens. Today capsulorhexis are done with a bent needle or with special forceps; the act of capsulorhexis is delicate, sometime un predicted and difficult to teach. The learning curve is relatively long and difficult. The proposed device enables a capsulorhexis which is round and has regular edges, done almost automatically and is predicted. The learning curve is short and easy. The capsulorhexis is done through the original operating wound with no need to widen it.