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Eye Diseases clinical trials

View clinical trials related to Eye Diseases.

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NCT ID: NCT05671120 Completed - Eye Diseases Clinical Trials

Transcutaneous Levator Recession for Non-thyroid Lid Retraction

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

This work aims to describe and assess the efficacy of transcutaneous levator palpebrea superioris muscle recession as a surgical procedure for treatment of upper lid retraction of various causes other than thyroid eye disease

NCT ID: NCT05660681 Completed - Dry Eye Disease Clinical Trials

Evaluation of the Tolerability and Efficacy of CWT-f-002 Lubricant Eye Drops

Start date: December 12, 2022
Phase: N/A
Study type: Interventional

The primary objective is to evaluate the tolerability and efficacy of CWT-f-002 lubricant eye drops in the treatment of the signs and symptoms of dry eye disease.

NCT ID: NCT05656027 Completed - Presbyopia Clinical Trials

Phase 3 Evaluation of the Safety and Efficacy of LNZ101 for the Treatment of Presbyopia

CLARITY
Start date: December 19, 2022
Phase: Phase 3
Study type: Interventional

Phase 3 study to evaluate the safety and effectiveness of LNZ101 for the treatment of Presbyopia.

NCT ID: NCT05629364 Terminated - Dry Eye Disease Clinical Trials

A Multi-Centre, Randomised, Controlled, Masked Phase 2 Study of the Safety and Efficacy of KIO-101 Ophthalmic Solution, Versus Vehicle Control in the Treatment of Dry Eye Disease in Patients With Autoimmune Disease

Start date: March 15, 2023
Phase: Phase 2
Study type: Interventional

A Multi-Centre, Randomised, Controlled, Masked Phase 2 Study of the Safety and Efficacy of KIO-101 Ophthalmic Solution, versus Vehicle Control in the treatment of Dry Eye Disease in Patients with Autoimmune Disease

NCT ID: NCT05627401 Recruiting - Thyroid Eye Disease Clinical Trials

Customized Multiple Orbital Wall Decompression for Sight-threatening Graves's Ophthalmopathy

Start date: January 1, 2021
Phase:
Study type: Observational

Graves' orbitopathy (GO) is an disfiguring and disabling autoimmune condition. Sight-threatening GO is an most severe form and occurs in about 5% of patients with Graves' disease. It can cause blurred vision, color vision and vision function damage, and affects the quality of life. The goal of this retrospective cohort study is to propose a customized orbital decompression algorithm for patients with sight-threatening Graves'ophthalmopathy and to explore the therapeutic effect of customized orbital decompression in sight-threatening patients.

NCT ID: NCT05622565 Recruiting - Image, Body Clinical Trials

Explainable Ocular Fundus Diseases Report Generation System

Start date: January 2011
Phase:
Study type: Observational

To establish a deep learning system of various ocular fundus disease analytics based on the results of multimodal examination images. The system can analyze multimodal ocular fundus images, make diagnoses and generate corresponding reports.

NCT ID: NCT05618730 Active, not recruiting - Dry Eye Clinical Trials

Safety, Tolerability, Plug Retention and Preliminary Efficacy of Tacrolimus-loaded Punctal Plug in Patients With Moderate to Severe Dry Eye Disease - Cohort B

Start date: September 29, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this interventional study is to assess safety, patient tolerability, plug retention rate, and preliminary efficacy in improving the symptoms of Dry Eye Disease (DED) of EXP-TC tacrolimus releasing punctal plug. The main questions it aims to answer are: 1. The safety of using EXP-TC plug following all study adverse events 2. The number of patients with Adverse Events related to the us of EXP-LP plug 3. The number of patients discontinuing the study due to plug discomfort 4. The total patients with plugs remained during the 3-months study duration from plug insertion 5. Exploratory: change from baseline in the study eye to follow-up visits in various Dryness clinical measurements. The change of measurements from baseline will also be compared between the study and fellow control eye (receiving artificial tears only, 0.15% sodium hyaluronate).

NCT ID: NCT05613517 Completed - No Eye Disorder Clinical Trials

Study of the Angle Lambda and Ocular Dominance

EPOLAF
Start date: November 25, 2022
Phase:
Study type: Observational

Anatomical ophthalmological connections and their dynamics are still debated in the scientific community. However, their considering is essential in many surgeries (strabismus, cataract, refractive...) or in clinical practice. The correlation between these biometric values would make it possible to refine the knowledge related to these landmarks and thus offer better ophthalmological management by integrating these variables into the clinical examination. The aim of the study is to analyze the correlation between the angle lambda and the ocular dominance depth in healthy individuals without ophthalmologic disorder. Then, seconds goals were defined as the study of the relation between the value of the angle lambda and the fixation disparity quantified with the Rousseau test. Relation between ocular dominance measured with the Guillon's test and the Hole-in-car test will also studied.

NCT ID: NCT05604651 Completed - Dry Eye Disease Clinical Trials

Comparison of Mucin Levels at the Ocular Surface of Visual Display Users With and Without Dry Eye Disease

Start date: March 1, 2021
Phase:
Study type: Observational

The study aimed to evaluate 1) if levels of the glycocalyx membrane mucins, including MUC1, MUC4, MUC16 and MUC20, are altered in conjunctival cells of visual display users With and Without Dry Eye Disease, and 2) if mucin levels correlate with dry eye clinical diagnostic data.

NCT ID: NCT05598437 Recruiting - Dry Eye Syndromes Clinical Trials

Prevalence of Different Etiologies of Ocular Dryness in Patients Previously Diagnosed With Dry Eye Disease in A Sample of Egyptian Patients

Start date: November 1, 2022
Phase:
Study type: Observational

Proposed Study Title: Prevalence of Different Etiologies of Ocular Dryness in Patients Previously Diagnosed with Dry Eye