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Extremity Fracture Lower clinical trials

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NCT ID: NCT06293469 Not yet recruiting - Clinical trials for Extremity Fracture Lower

Accelerated Flap Coverage in Severe Lower Extremity Trauma

FLAP ATTACK
Start date: May 2024
Phase: N/A
Study type: Interventional

The goal of this randomized controlled trial is to determine if accelerated flap coverage compared to standard flap coverage timing leads to improved infection-related complications in patients with open fractures and/or dislocations below the knee. Eligible patients will be randomized to receive either a flap within a goal of 72 hours of injury or standard of care flap timing for the institution. The primary outcome will be a composite outcome to evaluate clinical status 6 months after randomization. Components of the composite outcome will be hierarchically assessed in the following order: 1) all-cause mortality, 2) amputation related to injury, 3) re-operation for infection and/or flap complication (flap compromise, partial and/or complete flap failure), and 4) days in hospital, defined as days in an acute in-patient hospital (i.e., not rehab or nursing facility).

NCT ID: NCT04872400 Completed - Fractures, Bone Clinical Trials

Acute Application of Antibiotic Powder in Open Fracture Wounds

APOW
Start date: June 14, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study is to help determine the best treatment for severe injures like open fracture wounds. Some broken bone injuries can be more likely to get an infection. It is mostly due to the way they were injured. Surgical site infection in the orthopedic surgery population is a big public health issue. Wound infections result in both longer length of hospital stay and total cost of care. This study will be using an antibiotic called Vancomycin or Tobramycin in a powder form.

NCT ID: NCT03779425 Completed - Clinical trials for Extremity Fracture Lower

VR-Based Physical Therapy Pilot Study

VR-PT
Start date: March 9, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the feasibility and acceptability of using the virtual reality-based physical therapy platform in patients with extremity fracture.