Characterization of Hamstring and Quadriceps Neuromuscular Fatigue After Soccer Game

Exercise Clinical Trial

— QIF  

Official title:

Characterization of Hamstring and Quadriceps Neuromuscular Fatigue After Different Modality of Training in Soccer Players

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04943510
• Other study ID #: 8168
• Status: Recruiting
• Phase: Phase 2
• Start date: November 4, 2021
• Est. completion date: July 2023

Study information

• Verified date: April 2022
• Source: University Hospital, Strasbourg, France
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This is a monocentric study comparing hamstring and quadriceps neuromuscular fatigue after simulated soccer game, anaerobic and aerobic training sessions. The purpose of this study was:

1. To quantify the decrease of isometric force immediately after a simulate soccer game.

2. To characterize peripheral and central fatigue between hamstring and quadriceps muscles and described the kinetics of recovery after specific tasks of soccer training.

3. To compare the level neuromuscular fatigue induced by anaerobic and aerobic training.

4. To highlight correlation between neuromuscular fatigue and performance markers.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 15
• Est. completion date: July 2023
• Est. primary completion date: July 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 16 Years to 40 Years

Eligibility

Inclusion Criteria:

• male

• age limits: minimum: 16 ; maximum: 40 years old

• to be a soccer player, licensed to the French Football Federation

• affiliation to the social health insurance scheme

• signing an informed consent form

Exclusion Criteria:

• impossibility to give the subject enlightened information (subject in emergency situation, difficulties in understanding the study, …)

• subject under the protection of justice

• subject under guardianship or curatorship

• lower limbs musculotendinous or articular problems

• smoker or having been a smoker in the last 5 years

• subject wearing a pacemaker

• drug treatment in progress and impossibility to stop it within 7 days before the beginning of the study.

Related Conditions & MeSH terms

• Exercise
• Fatigue
• Neuromuscular Fatigue

Intervention

Other:
• Physical exercices
surface EMG: surface electrodes will be positioned on the muscles to evaluate the level of muscle activation non invasive muscular neurostimulations : application of a percutaneous electrical stimulation of the motor nerve of the considered muscle and a direct electrical stimulation of the muscle

Locations

Country	Name	City	State
France	Hopitaux Universitaires de Strasbourg	Strasbourg

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Strasbourg, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Difference in maximal isometric hamstring strength before and immediately after exercise (i.e., pre vs. immediate post exercise) expressed as a percentage (%).		Before and immediately post exercise (i.e., during the first minute after cessation of exercise)
Secondary	Relative difference (in %) in maximum isometric hamstring strength before and after exercise (i.e., pre- vs. post-exercise), relative to pre-exercise strength across different test types.		Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Secondary	Relative difference (in %) in maximal isometric quadriceps strength before and after exercise (i.e., pre vs. post exercise), related to preexercise strength according to the different types of tests.		Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Secondary	Relative difference (%) in maximum isometric hamstring and quadriceps strength for each test type at the different times of interest.		Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Secondary	Difference in pre- and post-exercise (i.e., pre- vs. post-exercise) hamstring potentiated jerk amplitude (N) relative to pre-exercise amplitude by event type at different times of interest.		Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Secondary	Difference in pre- and post-exercise (i.e., pre- vs. post-exercise) potentiated jerk amplitude (N) of the quadriceps, relative to pre-exercise amplitude, by test type at different times of interest.		Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Secondary	Difference in amplitude of the potentiated jerk (N) before and after exercise, related to the preexercise amplitude according to the muscle involved (hamstrings or quadriceps) and the type of test at different times of interest.		Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Secondary	Difference in the level of voluntary hamstring activation, expressed in newtons (N), before and after exercise, related to the pre-exercise action level, according to the type of test at different times of interest.		Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Secondary	Difference in the level of voluntary quadriceps activation, expressed in newtons (N), before and after exercise, related to the pre-exercise action level, according to the type of test at different times of interest.		Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Secondary	Difference in the level of voluntary action before and after exercise, related to the level of action before exercise, according to the muscle involved (hamstrings or quadriceps) and the type of test at different times of interest.		Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Secondary	Differences in overall fatigue, peripheral fatigue, and central fatigue of hamstrings versus quadriceps between exercise modalities.	Determine the modalities of exercises which induce the highest level of fatigue and characterize the etiology of neuromuscular fatigue (i.e., peripheral or central) for typical drills performed daily by elite soccer players	Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Secondary	Ratio (%) of initial to post-exercise values based on field indicators and neuromuscular fatigue.		Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise