Guayusa Extract on Exercise Training

Status Completed

Clinical Trial Summary

Guayusa extract is a caffeinated Amazonian 'super-leaf' belonging to the holly species that contains a very unique blend of polyphenol antioxidants and caffeine (~20% caffeine, 30% chlorogenic acids, 5% catechins). It is also remarkably low in tannins which are responsible for the bitter taste found in most teas - giving it a sweet flavor profile. As such, it is marketed as an ingredient that can help support energy and performance with potential health-related benefits due to its antioxidant properties. Indeed, ingredients such as these are often consumed by individuals prior to exercise in order to help improve exercise performance, or otherwise to support health-related goals. Whereas several studies have suggested that caffeine and chlorogenic acid consumption may improve performance, mood, and concentration, and some evidence in animals have linked catechin consumption to improved health outcomes, no studies have previous studied whether guayusa extract supplementation helps to support exercise performance in humans. In this study, we will test the whether dietary supplementation with the botanical organic guayusa extract helps support (1) the desire to exercise and exercise performance throughout a 6-week high intensity exercise training program, and thus (2) helps support the physiological adaptations (including body composition, fasting metabolic biomarkers, blood pressure and heart rate, submaximal and maximal exercise performance and fuel metabolism, and changes in the gut microbiome/mycobiome) to a 6-week high intensity exercise training program. Question 1: Does organic guayusa extract supplementation support the desire to train and training load in physically-active women performing a high-intensity exercise training program? Question 2: Does organic guayusa extract supplementation support physiological adaptation to exercise (including body composition, fasting metabolic biomarkers, blood pressure and heart rate, submaximal and maximal exercise performance and fuel metabolism, and changes in the gut microbiome/mycobiome) in physically-active women performing a high-intensity exercise training program?

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05820399
Study type	Interventional
Source	University of Iowa
Contact
Status	Completed
Phase	N/A
Start date	September 5, 2022
Completion date	November 18, 2022

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT04295590` - Impact of Augmenting Exercise Intensity vs. Frequency	N/A
Completed	`NCT05934578` - Lymphatic Function in Patients With Fontan Circulation: Effect of Physical Training	N/A
Completed	`NCT03563430` - Effects of Different Recovery Methods on Lactic Acid Removal, Flexibility, Strength, and Endurance	N/A
Not yet recruiting	`NCT06453473` - Transfer Effects of Stationary Bicycle Perturbation Training on Older Adults' Cycling Skills	N/A
Completed	`NCT02981667` - Higher Enjoyment in Response to High Intensity Interval Training Versus Moderate Intensity Continuous Exercise	N/A
Completed	`NCT05255497` - The Effect of Sensorial Biodex Balance Balance System Exercises in Diabetic Neuropathy	N/A
Completed	`NCT04084535` - Effects of High Intensity Interval Training (HIIT) vs. Inspiratory Muscle Training on the Recovery After a Maximal Apnea.	N/A
Completed	`NCT04384185` - Combined Treatment of Manual Therapy and Therapeutic Exercise in Patients With Low Back Pain	N/A
Completed	`NCT04114175` - Spinal Stabilization Exercises in Individuals With Transtibial Amputatıon	N/A
Completed	`NCT02958657` - Effect of Exercise on Platelet Reactivity After Myocardial Infarction	N/A
Not yet recruiting	`NCT00808600` - Empowerment of Lung and Heart-lung Transplant Patients	N/A
Completed	`NCT04450134` - Histamine H1/H2 Receptors and Training Adaptations	N/A
Completed	`NCT02999139` - Analytic, Prospective Cohort Study of Athletes Enrolled in an Exercise Training Intervention
Not yet recruiting	`NCT04366414` - Breathing Protocol in Breath-hold Divers	N/A
Recruiting	`NCT04311736` - Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in At-risk Older Adults	N/A
Recruiting	`NCT03754478` - Follow-Up of Fitness in Overweight Patients Treated With Physical Activity
Completed	`NCT05402527` - Fish Nutrient Supplementation in High-intensity Functional Training	N/A
Completed	`NCT06138951` - Exercise Dose-response and Protein Requirements	N/A
Recruiting	`NCT06260579` - Home-based Exercise and Physical Activity Intervention After Kidney Transplantation: Impact of Exercise Intensity	N/A
Completed	`NCT05396963` - Egg White Supplementation in High-Intensity Functional Training	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.