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Exercise Physiology clinical trials

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NCT ID: NCT05269615 Recruiting - Exercise Physiology Clinical Trials

Exercise-induced Erythropoiesis: the Mechanistic of Angiotensin II

Start date: March 20, 2023
Phase: Phase 4
Study type: Interventional

The major aims are to determine the effect of acute (single dose) blockade of ANGII receptor 1 (AT1) on the EPO response to a single session of endurance exercise, as well as determine the effect of chronic (8-week) blockade of AT1 on ET-induced adaptations in total circulating red blood volume and hemoglobin.

NCT ID: NCT04854356 Recruiting - Biomechanics Clinical Trials

Blood Flow Restriction During High-intensity Interval Exercise

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The study is a randomized controlled trial aimed to compare the effects of blood flow restriction (BFR) in different phases (i.e., exercise versus interval) during high-intensity interval exercise (HIIE) on aerobic capacity, anaerobic capacity, isokinetic knee strength, lower limb biomechanics during single-leg landing and cycling economy among healthy adult males. Participants were randomized to three groups. Intervention was conducted for 12 weeks with 2 sessions per week. During intervention, all groups conducted HIEE on cycle ergometer with or without BFR. Assessments were conducted before the intervention, on the 6th week of intervention and after the intervention. Assessments included physical characteristics, aerobic and anaerobic capacity, lower limb biomechanics during single-leg landing and isokinetic knee strength.

NCT ID: NCT03794050 Terminated - Exercise Physiology Clinical Trials

Comparing Acute Aerobic and Resistance Exercise

CAARE
Start date: December 18, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effect of age and fitness level on the physiological response to an acute bout of resistance or aerobic exercise.

NCT ID: NCT03789045 Completed - Exercise Physiology Clinical Trials

Metabolic Thresholds and Fat Utilization Points Correlation

MATDFP
Start date: May 1, 2016
Phase:
Study type: Observational

To examine existence of connection between fat utilization points, both maximal and minimal with individual metabolic thresholds in different subjects. As a consequence, this innovative approach could offer a supplementary method for both aerobic and anaerobic thresholds detection as well as useful and practical exercise intensity selection marker.

NCT ID: NCT03569566 Completed - Exercise Physiology Clinical Trials

Performance Determinants Factors in Elite Endurance Athletes.

Start date: June 27, 2018
Phase:
Study type: Observational

Several studies have investigated determinant factors for endurance performance among different athletes, untrained individuals and patients focusing on the impact of age, genes and training intensity. A further step in this research will be to investigate the impact of age, genes, training intensity and history of tick-bourne disease on endurance performance in elite endurance athletes. We are planning a project with a two-step model. In step one we will, in a cross-sectional study design, investigate potential relationships between age, training intensity, training volume, genes, exosomes and history of tick-bourne disease and physiological variables and endurance performance. In step two we will investigate differences in training adaptation by observing and monitoring all training done by the participants during a 6-months period. The participants will be tested for several physiological variables before, after 3- months and after this period. We will also investigate the impact of age, training intensity, training volume, genes and history of tick-bourne disease on the results from the physiological tests and performance.

NCT ID: NCT01906333 Completed - Diabetes Clinical Trials

Elevated FFA and Skeletal Muscle Lipid Content

Start date: May 2013
Phase: N/A
Study type: Interventional

There is increasing evidence that skeletal muscle lipid content (IntraMyoCellular Lipid, IMCL) markedly increases the risk of metabolic complications, including insulin resistance and cardiovascular events. The investigator hypothesizes that skeletal muscle is passively taking up FFAs when the availability is high, thereby leading to an increased storage. To test this hypothesis, the investigator wants to manipulate FFA levels, by means of exercise, and monitor intramuscular lipid content. Therefore the objective is to examine the effect of an exercise-induced elevation of FFA on skeletal muscle lipid content in healthy lean men. To this end, skeletal muscle lipid content will be investigated at baseline and after an exercise protocol and again after a four-hour recovery period from exercise, once in a condition with high FFA concentration, once with low FFA concentration. To achieve high- versus low FFA concentrations, an exercise protocol was chosen and participants had to perform this protocol once with a glucose supplementation and once without. Skeletal muscle lipid content will be determined before, directly after exercise and 4 h post exercise (from muscle biopsies) with or without glucose supplementation.