Exercise Performance Clinical Trial
Official title:
The Effects of Isotonic Beetroot Supplementation on Sprint Interval Exercise Performance.
This study aims to examine the effects of dietary nitrate supplementation via beetroot juice on sprint interval cycling exercise performance. Twenty-four participants (male or female) will undertake a randomized, crossover trial where they consume either (i) an isotonic beetroot juice drink containing nitrate (12.9 mmol) for 5 days or (ii) an isotonic sports drink (no nitrate) for 5 days. On Day 5 of each trial, participants will come to the laboratory and 2 hours after consuming their allocated drink will complete a 6 bouts of sprint interval exercise. Power output during cycling will be measured as the primary outcome measure. Salivary and plasma measures of nitrate and nitrite will be taken over the course of the morning on Day 5. After a 5-day washout period participants will crossover and begin their second trial.
Status | Recruiting |
Enrollment | 24 |
Est. completion date | February 28, 2025 |
Est. primary completion date | February 28, 2025 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 21 Years to 40 Years |
Eligibility | Inclusion Criteria: - Age: 21 - 40 years - Healthy and injury-free (e.g., no cardiovascular disease, diabetes mellitus, orthopaedic impairment that interferes with moderate-to-vigorous exercise) - Blood pressure < 130/90 mmHg - Be physically active: Engaging in a minimum of 150 minutes of moderate-intensity exercise or 75 minutes of vigorous-intensity physical activity each week. - Recreational cyclist (Minimum 1 hour cycling per week). - Body mass index: 18.5-25 kg/m2 - Non-smoker - Asian Exclusion Criteria: - Any allergies to beetroot or isotonic drink. - Asthma - Any diagnosed form of cardiometabolic disease (heart disease, stroke, peripheral vascular disease, diabetes, metabolic syndrome, high blood pressure). - Any symptoms contraindicating exercise testing (e.g. chest pains). - Any balance or dizziness problems. - Any chronic medical conditions (whether medicated or not). - Any bone joint problems. - Any Physician diagnosed contraindications to exercise. - Any other health problems that may be a cause for concern or contraindication to exercise. - Any recent Covid vaccination (within last 2 weeks). |
Country | Name | City | State |
---|---|---|---|
Singapore | Human Bioenergetics Laboratory, National Institute of Education, Nanyang Technological University | Singapore |
Lead Sponsor | Collaborator |
---|---|
Nanyang Technological University |
Singapore,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Power output during maximal sprint cycling | Peak and mean power output | 2 hours after drink ingestion | |
Secondary | Salivary nitrate | Salivary nitrate/nitrite concentration | Pre-drink, 2 hours post-drink and immediately post-exercise (2.5 hours post-drink) | |
Secondary | Plasma nitrate and nitrite | Plasma nitrate and nitrite | Pre-drink and 2 hours post-drink | |
Secondary | Muscle oxygenation | Near infra-red spectroscopy | During exercise (2-2.5 hours post drink) | |
Secondary | Sensory evaluation (Acceptance and Preference Test Evaluation by Meilgaard et al 2007) | Drink taste and perception (7-point scale - 1 extremely dislike to 7 extremely like) | Immediately post-drink (1 minute post-drink) | |
Secondary | Stroop test | Reaction time and correct answers | Immediately pre- (2 hours post-drink) and immediately post-exercise (2.5 hours post drink) |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
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