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Exercise, Aerobic clinical trials

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NCT ID: NCT05514392 Recruiting - Exercise, Aerobic Clinical Trials

The Effect of Bicycle Ergometer Training on Balance and Emg Activity

Start date: September 15, 2022
Phase:
Study type: Observational

The study will contribute to answering the question of 'in which exercise types of single-leg and double-leg exercise protocols will affect whether fatigue occurs early or not, and muscle activations will occur. In response to this question, clinicians will prefer to focus on which type of exercise produces more muscle activation and late fatigue. Few studies have been done on single and double leg bicycle ergometers in the literature. From these studies; While examining the lactate and EMG threshold values after cycling ergometer training, another study compared the effectiveness of single and double leg cycling ergometers. In the literature, EMG and dynamic balance were not used in the comparison after single and double leg bicycle ergometer training. In this study, the effectiveness of single and double legged bicycle ergometers will be compared by looking at EMG and dynamic balance changes.

NCT ID: NCT04476576 Recruiting - Cardiotoxicity Clinical Trials

Aerobic Exercise is Cardio-protective in Hemato-oncological Disease and New-onset Chemotherapy

AEROHEMONCO
Start date: March 2, 2021
Phase: N/A
Study type: Interventional

Oncological diseases are the main cause of death in developed countries and also in Uruguay. Advances in therapeutics have made possible to aspire to cure and in other cases long-term remission with a significant increase in survival and the transformation of cancer into a chronic disease. Chemotherapy treatments have some side effects and cardiotoxicity is well known within them. Heart failure (HF) is a progressive pathology, with high mortality and high resource requirements of the health system with a prognosis that may be worse than some types of cancers. The treatment of established systolic dysfunction and symptomatic HF is mainly based on the indication of inhibitors of the angiotensin-converting enzyme and beta-blockers among other pharmaceutical and no pharmaceutical interventions. Aerobic physical exercise, as a therapeutic intervention, reverses the physiopathological changes that are presumed to lead to HF in sedentary people and it is known, it is feasible to execute an exercise program in cancer patients. However, effective treatments for the primary prevention of systolic dysfunction are not well known. Our hypothesis is that an aerobic physical exercise program for at least 3 months, in subjects with lymphoma and new-onset chemotherapy, is effective in preventing left ventricular systolic dysfunction, at the end of chemotherapy and at one year. For this, the investigators propose a randomized, controlled, clinical study which is blind both for the patient and the evaluating physician, comparing the difference of global longitudinal strain (an echocardiographic result of myocardial function) pre-chemotherapy minus end of chemotherapy and minus one year after, between the active group (aerobic program) and the control group (flexibility program).

NCT ID: NCT04258969 Withdrawn - Colorectal Cancer Clinical Trials

Pedaling at a Low-Moderate Intensity During Chemotherapy Administration

Start date: December 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the feasibility of completing a low-moderate intensity pedaling session concurrent to chemotherapy treatment for colorectal cancer. Secondary objectives for this study consist of evaluating the role of pedaling on sarcopenia rates, quality of life markers, chemotherapy side effects, rate of hospital admissions, and treatment delays.

NCT ID: NCT04127318 Withdrawn - Immunotherapy Clinical Trials

Low-moderate Intensity Pedaling During Immunotherapy Administration

Start date: January 31, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the feasibility pedaling using an under-the desk bike during immunotherapy infusions. Also, the study hopes to evaluate how pedaling impacts quality of life and treatment response biomarkers. Lastly, the study will evaluate the relationships between treatment response and muscle mass which is evaluated with computerized tomography (CT) scans.

NCT ID: NCT02796599 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Interfaces of Non-invasive Ventilation on Performance in Patients With Chronic Obstructive Pulmonary Disease

Exercise-NIV
Start date: June 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine wether the interface (facial or nasal mask) influences performance in patients with chronic obstructive pulmonary disease exercising with non-invasive ventilation.

NCT ID: NCT01561404 Terminated - Muscle Strength Clinical Trials

Effect of the Inhibition of the Mammalian Target of Rapamycin on Metabolism and Exercise

EXETOR
Start date: September 2011
Phase: Phase 4
Study type: Interventional

This is an exploratory study based on the hypothesis that kidney transplant patients treated with an immunosuppressive therapy based on an inhibitor of the mammalian target of rapamycin (m-TOR) may increase resistance to physical exercise, which would result in an improvement in the quality of life of these patients.