Executive Dysfunction Clinical Trial
Official title:
Prefrontal Modulation by Repetitive Bilateral Transcranial Direct Current Stimulation (tDCS) in Crack-cocaine Addicted Inpatients.
In this study, eligible crack-cocaine addicted inpatients recruited from specialized clinics
for substance abuse disorder treatment, filling inclusion criteria and not showing any
exclusion criteria, were randomized to receive the repetitive (10 sessions, every other day)
bilateral dorsolateral Prefrontal Cortex (dlPFC: cathodal left / anodal right) tDCS (2
milliamperes, 3x7 cm2, for 20 min) or placebo (sham-tDCS). Craving to the use of
crack-cocaine was examined before (baseline), during and after the end of the tDCS treatment.
Based in our previous data, our hypothesis was that repetitive bilateral tDCS over dlPFC
would favorably change clinical, cognitive and brain function in crack-cocaine addiction and
these would be long-lasting effects.
Before (baseline) and after tDCS or sham-tDCS treatment, subjects were examined:
(1) clinically, regarding craving (obsessive compulsive scale) and relapses to the drug use.
They were followed-up for clinical examination at least 60 days after treatment.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04111549 -
GOALS Cognitive Training Delivered to Aging Veterans in Person or Via Telehealth
|
N/A | |
| Completed |
NCT02122198 -
Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women
|
N/A | |
| Enrolling by invitation |
NCT05017779 -
A Hybrid Effectiveness-implementation Trial of a High School-based Executive Function Treatment for Autistic Youth
|
N/A | |
| Terminated |
NCT02416193 -
Can Vitamin D3 Improve Cognitive Function in Individuals With Type 2 Diabetes? (THINK-D)
|
Phase 2 | |
| Completed |
NCT02613936 -
Transcranial Direct Current Stimulation for the Treatment of Deficits After Traumatic Brain Injury
|
N/A | |
| Recruiting |
NCT05874791 -
Executive Control Training for Adolescents With ADHD: A Randomized Controlled Effectiveness Trial
|
N/A | |
| Recruiting |
NCT04465708 -
HOPS Study: A Conceptual Replication
|
N/A | |
| Active, not recruiting |
NCT05131659 -
Intervention-Induced Plasticity of Flexibility and Learning Mechanisms in ASD
|
N/A | |
| Active, not recruiting |
NCT04121650 -
Executive Function and Symptom Reduction in Youth Receiving Home-based Treatment With Collaborative Problem Solving
|
||
| Completed |
NCT04221841 -
Executive Functions and Reinforcement Sensitivity in Women With Obsessive Compulsive Symptoms
|
||
| Completed |
NCT03285347 -
Effect of Computer-based Cognitive Training on Attention and Executive Functions in Patients With Parkinson's Disease
|
N/A | |
| Completed |
NCT03490110 -
Brain Markers of Improvements in Cognitive Functioning
|
N/A | |
| Completed |
NCT03073122 -
The Boston Circulatory Arrest Study: Antecedents and Correlates of Well-Being in Adults With Congenital Heart Disease
|
||
| Completed |
NCT03958487 -
An Executive/Monitoring Treatment Protocol on Everyday Life Activities
|
N/A | |
| Completed |
NCT02091284 -
Bilateral Prefrontal Modulation in Alcoholism
|
N/A | |
| Completed |
NCT01730261 -
Online Emotional Regulation Group Treatment
|
Phase 1 | |
| Completed |
NCT00271596 -
Citalopram to Enhance Cognition in HD
|
Phase 2 | |
| Active, not recruiting |
NCT04108728 -
Neuropsychological Development and Executive Functioning of Children Born to HIV- Infected Mothers ( NEUROPSY-HEU )
|
N/A | |
| Active, not recruiting |
NCT04105530 -
Transcranial Direct Current Stimulation of the Temporal Cortex in Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)
|
N/A | |
| Enrolling by invitation |
NCT05135728 -
Development and Pilot Testing of a Novel Preschool Executive Function Curriculum
|
N/A |