Advanced Cancer Clinical Trial
Official title:
Decision to Limit or Withdraw Specific Therapies for Advanced Cancer and Hematological Malignancies : Physicians and Patients Points of View and Interactions.
The decision to limit or withdraw specific therapies (DLWT) in patients with advanced cancer is a complex process that is always painful for patients, relatives and professionals. For more than 10 years, shared decision making has been more and more emphasized. However, few data in the literature rely on clinical research. In order to understand their difficulties and issues, this study explores the determinants and modalities of DLWT and analyses the feasibility of different methods for investigating this decision making process.
This study explores the decision-making process for patients with advanced cancer when the
question to imit or withdraw specific therapies (DLWT) is raised, with a cross-analysis of
physicians and pts points of view.
This study took place in 5 oncology and hematology units : 2 university hospitals, 1 general
hospital, 1 cancer center and 1 private hospital. The study included two different
approaches: an epidemiological section to identify the prevalence of these situations in
different institutions and a qualitative study section exploring factors influencing the
decision process. The epidemiological analysis included all hospitalized patients identified
with advanced cancer for whom the question of DLWT was raised in a given week or during the
two weeks preceding the investigation.
The qualitative analysis was based on interviews with the referent oncologist (or
hematologist) and his patient (conducted by a physician and a psychologist respectively) as
well as interviews with other partners involved in the situation (care staff and relatives)
depending on the center. Researchers also participated in multidisciplinary meetings and
monitored changes in the decision over a three month period.
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Intervention Model: Single Group Assignment, Masking: Open Label
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