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Clinical Trial Summary

Deep Brain Stimulation (DBS) is a well established therapy in medication-refractory essential tremor (ET). Since the inception of DBS, cathodic pulses are used. Recent work suggests that biphasic pulses influence the therapeutic window when compared to cathodic pulses, when tested acutely. Animal studies and work from cochlear implants, show that the use of an interphase gap, influences the generation of action potentials. In this study, the goal is to investigate the use of an interphase gap in biphasic pulses in DBS for ET patients.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05177900
Study type Interventional
Source KU Leuven
Contact Alexandra Boogers
Phone +3216343143
Email [email protected]
Status Recruiting
Phase N/A
Start date December 1, 2021
Completion date August 31, 2022

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