Clinical Trials Logo

Clinical Trial Summary

Deep Brain Stimulation (DBS) is a well established therapy in medication-refractory essential tremor (ET). Since the inception of DBS, cathodic pulses are used. Recent work suggests that biphasic pulses influence the therapeutic window when compared to cathodic pulses, when tested acutely. Animal studies and work from cochlear implants, show that the use of an interphase gap, influences the generation of action potentials. In this study, the goal is to investigate the use of an interphase gap in biphasic pulses in DBS for ET patients.

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT05177900
Study type Interventional
Source KU Leuven
Contact Alexandra Boogers
Phone +3216343143
Email [email protected]
Status Recruiting
Phase N/A
Start date December 1, 2021
Completion date August 31, 2022

See also
  Status Clinical Trial Phase
Recruiting NCT05101161 - Neurofeedback Using Implanted Deep Brain Stimulation Electrodes N/A
Terminated NCT02678429 - Atlas Predicted DBS Settings in Essential Tremor Phase 4
Terminated NCT02894567 - Evaluation of Directional Recording and Stimulation Using spiderSTN N/A
Completed NCT02523807 - Tremor Monitoring Device N/A
Active, not recruiting NCT02255929 - Gamma Knife Radiosurgery for Treatment of Essential Tremor N/A
Completed NCT02277106 - Evaluate SAGE-547 in Patients With Essential Tremor Phase 2
Completed NCT01223144 - Decision-making and Emotion Recognition in Essential Tremor N/A
Completed NCT00906412 - Ventrointermediate Nucleus (VIM DBS) and Working Memory N/A
Completed NCT03051178 - Wearable Sensor for Responsive DBS for ET N/A
Recruiting NCT03795935 - Relief From Side Effects: Clinical Use of Electrodes With Direction N/A
Recruiting NCT04501133 - Sensory-specific Peripheral Stimulation for Tremor Management N/A
Active, not recruiting NCT03560622 - Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomy N/A
Completed NCT00368199 - Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes N/A
Recruiting NCT05106816 - The Effects of Vibrotactile Stimulation in Patients With Movement Disorders N/A
Recruiting NCT04720469 - A Second Magnetic Resonance Guided Focused Ultrasound Thalamotomy for Essential Tremor N/A
Completed NCT01468948 - Octanoic Acid for Essential Tremor Phase 1
Recruiting NCT04032470 - Boston Scientific Registry of Deep Brain Stimulation for Treatment of Essential Tremor (ET)
Not yet recruiting NCT04265209 - [18F] LBT-999 PET Compared to [123I]-FP/CIT SPECT to Distinguish Between Parkinson's Diseases and Essential Tremor Phase 3
Completed NCT02947841 - The Effectiveness of Alternating Stimulation in Preventing Tolerance in Essential Tremor Patients N/A
Active, not recruiting NCT02668146 - An Efficacy/Safety Study of Perampanel for Reducing Essential Tremor Phase 2