Cyclic Deep Brain Stimulation in Essential Tremor

Status Recruiting

Clinical Trial Summary

The aim of the study is to prove the efficacy and safety of cyclical deep brain stimulation (DBS) in patients with essential tremor, and demonstrate non-inferiority of cyclical DBS on tremor control when compared to continuous stimulation.

Clinical Trial Description

This study is a prospective, randomized, double-blind cross-over trials. Patients will be randomized into two groups in a cross-over fashion to have either continuous or cyclical stimulation for a total of three months. Following this, the trial will be unblinded and open-label follow up will continue for another nine months. Device use as per standard practice continues after the end of the trial. If the hypothesis is proven correct, this will provide proof of concept that cyclical stimulation for the treatment of essential tremor results in improved battery life, reduced number of operations for battery changes, reduction in stimulation side-effects and enhancing quality of life. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04260971
Study type	Interventional
Source	King's College Hospital NHS Trust
Contact	Kantharuby Tambirajoo, MD
Phone	00442032991906
Email	kantharuby.tambirajoo@nhs.net
Status	Recruiting
Phase	N/A
Start date	February 25, 2020
Completion date	December 31, 2022

View Details

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