Limb Cooling in Essential Tremor

Status Completed

Clinical Trial Summary

Essential Tremor (ET) is characterized by tremors affecting the arms. The investigators will examine the effects of non-pharmacological limb cooling on clinical and physiological characteristics in patients presenting with ET at three different temperatures; and will measure changes in tremor amplitude after cooling of the upper limb.

Clinical Trial Description

Once the subject has agreed to participate in the study the following assessments will be performed.

Three non-pharmacological assessments will be performed at different temperature to the upper limbs. The first will be a baseline assessment with upper limbs maintaining a normal body temperature (96-98°F). The second assessment will be performed with upper limbs at a temperature of 59°F and the third will be performed at a temperature of 80°F for a period of 10 minutes. At the end of 10 minutes, tremor measurements will be 15, 40, and 60 minutes.

1. Assessments will include the Tremor Rating Scale (TRS), Handwriting Assessment Battery (HAB) and the Functional Dexterity Test (FDT).

2. The Bagnoli and Trigno EMG systems will record surface EMG signals from muscles and accelerometer readings. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02067702
Study type	Observational
Source	University of Florida
Contact
Status	Completed
Phase
Start date	October 2014
Completion date	January 14, 2019

View Details

See also
Status	Clinical Trial	Phase
Withdrawn	`NCT05381688` - VIM DBS Respiratory Modulation: N-of-1 Trial
Recruiting	`NCT05101161` - Neurofeedback Using Implanted Deep Brain Stimulation Electrodes	N/A
Completed	`NCT02277106` - Evaluate SAGE-547 in Participants With Essential Tremor	Phase 2
Recruiting	`NCT05769933` - Bridging Gaps in the Neuroimaging Puzzle: New Ways to Image Brain Anatomy and Function in Health and Disease Using Electroencephalography and 7 Tesla Magnetic Resonance Imaging
Terminated	`NCT02894567` - Evaluation of Directional Recording and Stimulation Using spiderSTN	N/A
Terminated	`NCT02678429` - Atlas Predicted DBS Settings in Essential Tremor	N/A
Completed	`NCT02523807` - Tremor Monitoring Device	N/A
Active, not recruiting	`NCT02255929` - Gamma Knife Radiosurgery for Treatment of Essential Tremor	N/A
Completed	`NCT01223144` - Decision-making and Emotion Recognition in Essential Tremor	N/A
Completed	`NCT00906412` - Ventrointermediate Nucleus (VIM DBS) and Working Memory	N/A
Recruiting	`NCT05214222` - Penpulimab Plus Chemotherapy With/Without Anlotinib for Patients With Advanced Esophageal Squamous Cell Carcinoma	Phase 2
Completed	`NCT03051178` - Wearable Sensor for Responsive DBS for ET	N/A
Recruiting	`NCT03795935` - Relief From Side Effects: Clinical Use of Electrodes With Direction	N/A
Not yet recruiting	`NCT06036368` - Study to Evaluate Safety and Efficacy of Peroneal Transcutaneous NeuroModulation in Subjects With Parkinson's Disease and Essential Tremor	N/A
Recruiting	`NCT05897775` - Coordinated Reset Deep Brain Stimulation for Essential Tremor	Phase 1
Recruiting	`NCT05968976` - Multicentre RCT of Awake Versus Asleep Tractography Based DBS for ET	N/A
Completed	`NCT06314139` - Tolerability and Efficacy of Continuous Theta-burst Stimulation for Essential Tremor: A Randomized Study.	N/A
Recruiting	`NCT04501133` - Sensory-specific Peripheral Stimulation for Tremor Management	N/A
Active, not recruiting	`NCT03560622` - Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomy	N/A
Completed	`NCT00368199` - Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes	N/A