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Essential Hypertension clinical trials

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NCT ID: NCT01132768 Terminated - Clinical trials for Essential Hypertension

The Confirmatory Olmesartan Plaque Regression Study

CONFIRM
Start date: May 2010
Phase: Phase 4
Study type: Interventional

Effect of olmesartan medoxomil (20-40 mg) on plaque regression in hypertensive patients with carotid atherosclerosis.

NCT ID: NCT01131546 Completed - Clinical trials for Essential Hypertension

Efficacy and Safety of Levamlodipine Besylate Compared to Amlodipine Maleate in Patients With Essential Hypertension

Start date: December 2009
Phase: Phase 4
Study type: Interventional

This study is designed to compare the safety and efficacy of levamlodipine besylate (2.5mg or 5mg) versus amlodipine maleate (5mg) in patients with mild to moderate essential hypertension.

NCT ID: NCT01127139 Completed - Clinical trials for Essential Hypertension

Effectiveness and Patient Self-assessed Compliance of Blood Pressure Treatment With Tarka® Fixed Combination in Patients With Essential Hypertension

Start date: April 2010
Phase: N/A
Study type: Observational

The fixed combination of verapamil SR/trandolapril (Tarka®) is an effective, well-tolerated therapy for the treatment of essential hypertension in those who require more than one agent to achieve optimal blood pressure (BP) control. The endpoint is compliance with Tarka® treatment by number/percentage of patients continued on fixed combination Tarka therapy after six months. This Post Marketing Observational Study will be conducted in a prospective, single-arm, single-country, multicenter format. The investigational sites will be the cardiologists, the doctors of internal medicine and general practicians. Since this will be a Post Marketing Observational Study, Tarka® will be prescribed in usual manner in accordance with the terms of the local market authorization with regards to dose, population and indication as well as the local guidelines.

NCT ID: NCT01122251 Completed - Clinical trials for Essential Hypertension

Efficacy and Safety of Lercanidipine and Valsartan in Patients With Essential Hypertension

Start date: December 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of fixed combination of lercanidipine (10 mg or 20 mg) and valsartan (80 mg or 160 mg), lercanidipine and valsartan alone in reducing blood pressure. The study will investigate the dose response relationship for the combinations and monotherapies.

NCT ID: NCT01120990 Completed - Clinical trials for Essential Hypertension

Hybrid Blood Pressure Monitor Validation

NISSEI
Start date: April 2010
Phase: Phase 4
Study type: Interventional

Assessment of the accuracy of a Blood Pressure Measuring Device with a digital display-column, NISSEI DM 3000, according to an adaptation of the "European Society of Hypertension International Protocol Revision 2010 for the Validation of Blood Pressure Measuring Devices in Adults".

NCT ID: NCT01113047 Completed - Clinical trials for Essential Hypertension

Aliskiren in Combination With Amlodipine in Hypertensive Patients Not Responding to Angiotensin Receptor Blocker (ARB) Plus Amlodipine

AWESOME
Start date: May 2010
Phase: Phase 3
Study type: Interventional

This study will assess the efficacy and safety of the single pill combination of Aliskiren and Amlodipine in patients with moderate hypertension not adequately responding to a single pill combination of Olmesartan and Amlodipine. Further this study will also assess the efficacy and safety of a single pill combination of Aliskiren, Amlodipine and Hydrochlorothiazide (HCTZ) in patients with moderate hypertension not adequately responding to a single pill combination of Aliskiren and Amlodipine.

NCT ID: NCT01093807 Completed - Clinical trials for Essential Hypertension

Efficacy and Safety of Lercanidipine and Enalapril in Patients With Essential Hypertension

FELT
Start date: March 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of various dosage combinations of lercanidipine (10 and 20 mg)and enalapril (10 and 20 mg) in comparison with their respective components and with placebo.

NCT ID: NCT01083017 Completed - Hypertension Clinical Trials

Resistant Arterial Hypertension Cohort Study

RAHyCo
Start date: April 2011
Phase:
Study type: Observational

The purpose of this study is to investigate the epidemiology of resistant hypertension, evaluate the efficacy and feasibility of a standardized drug treatment regimen (including the randomization of two doses of the diuretic used - chlorthalidone), study two interventions in the group of patients that is non-compliant, and study environmental and genetic variables of individuals with resistant hypertension in a family design.

NCT ID: NCT01042392 Completed - Clinical trials for Essential Hypertension

Efficacy of Aliskiren Compared to Ramipril in the Treatment of Moderate Systolic Hypertensive Patients

ALIAS
Start date: November 2009
Phase: Phase 4
Study type: Interventional

This prospective multicenter, double blind study will evaluate the efficacy and safety of aliskiren versus ramipril in patients with moderate systolic essential hypertension.

NCT ID: NCT01033071 Completed - Clinical trials for Essential Hypertension

Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone Compared to Olmesartan Medoxomil and Hydrochlorothiazide in Participants With Moderate to Severe Hypertension.

Start date: January 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the antihypertensive effect of azilsartan medoxomil plus chlorthalidone, once daily (QD), to olmesartan medoxomil plus hydrochlorothiazide in participants with moderate to severe hypertension.