Clinical Trials Logo
  1. Home
  2. Esophageal Neoplasms
  3. NCT02182804
  4. Details
NCT02182804 Clinical Trial

A Diagnostic Study of the Advanced Endoscopy to Detect Early Esophageal Cancer

Esophageal Neoplasms Clinical Trial

Official title:
Diagnostic Values of Probe-based Confocal Laser Endomicroscopy (pCLE) and Magnifying Narrow Band Imaging (M-NBI) for Early Neoplasms Detection in Esophageal Lugol'S-voiding Lesions.

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02182804
Other study ID # RP008
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date February 2013
Est. completion date June 2014

Study information
Verified date August 2020
Source King Chulalongkorn Memorial Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This descriptive cross sectional study aims to directly compare the diagnostic capability of the probed-based confocal laser endomicroscopy (pCLE) and the magnifying narrow band imaging (M-NBI) in the Lugol's voiding lesions.

Recruitment information / eligibility
Status Completed
Enrollment 44
Est. completion date June 2014
Est. primary completion date June 2014
Accepts healthy volunteers No
Gender All
Age group 20 Years and older
Eligibility Inclusion Criteria:

- Age over 20 years

- Having histological-confirmed diagnosis of head and neck cancer

- Having no esophageal symptoms

Exclusion Criteria:

- Having index cancer of nasopharynx

- History of esophageal surgery

- Having esophageal stricture or obstruction

- Having esophageal varices

- Known case of esophageal cancer

- Uncorrectable coagulopathy and thrombocytopenia

- Pregnancy

- Thyrotoxicosis

- Creatinine clearance less than 30 ml/min

- Allergy to iodine or fluorescein.

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• Olympus
narrow band imaging with magnification
• Cellvizio
probe-based confocal laser endomicroscopy

Locations
Country Name City State
n/a

Sponsors (2)
Lead Sponsor Collaborator
King Chulalongkorn Memorial Hospital Chulalongkorn University

Outcome
Type Measure Description Time frame Safety issue
Primary Accuracy Diagnostic performance of the pCLE and M-NBI in Lugol's voiding lesions size larger than 5 millimeters. an expected average of 2 weeks
See also
  Status Clinical Trial Phase
Not yet recruiting NCT05013697 - TQB2450 Solution for Injection (TQB2450)+Paclitaxel+Cisplatin ± Anlotinib in the Treatment of Esophageal Cancer. Phase 2
Completed NCT02253602 - Innovative MRI Techniques to Improve Treatment Stratification of Patients With Esophageal Cancer N/A
Completed NCT02128243 - Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer Phase 2
Completed NCT01900691 - Removal of the Evolution® Esophageal Stent - Fully Covered N/A
Completed NCT01719926 - Phase I Platinum Based Chemotherapy Plus Indomethacin Phase 1
Terminated NCT01572987 - Endoscopic Resection or Ablation for Patients With Dysplasia or Cancer Requiring Treatment of Barrett's Esophagus N/A
Terminated NCT00760604 - A Phase III Study of En Bloc Versus Non-En Bloc Esophagectomy in Esophageal Cancer Phase 3
Completed NCT00160030 - Study Comparing Radiochemotherapy With Folfox 4 Regimen or 5FU-Cisplatin in Patients With Inoperable Esophageal Cancer Phase 2
Suspended NCT00048529 - Study of T900607-Sodium in Subjects With Previously Treated Gastric Cancer or Adenocarcinoma of the Esophagus Phase 2
Recruiting NCT05007106 - MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) Phase 2
Completed NCT02284802 - Early Detection of Tumors of the Digestive Tract by Confocal Endomicroscopy N/A
Terminated NCT03223662 - Metabolomic and BH3 Profiling of Esophageal Cancers: Identification of Novel Assessment Methods of Treatment Response for Precision Therapy Phase 2
Completed NCT05680077 - KCNA3 and OTOP2 Gene Methylation Combined Detection Kit (Fluorescent PCR Method)
Completed NCT03549494 - Evaluation of Ocoxin®-Viusid® in Advanced Stomach Cancer and Gastric Esophagogastric Junction Phase 2
Completed NCT03261947 - A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and Other Advanced Solid Tumors Phase 2
Terminated NCT00094978 - Depsipeptide/Flavopiridol Infusion for Cancers of the Lungs, Esophagus, Pleura, Thymus or Mediastinum Phase 1
Recruiting NCT02908204 - Long-term Outcomes of Superficial Esophageal Squamous Cell Carcinoma N/A
Completed NCT02703142 - Endoscopic Evaluation After Esophagectomy N/A
Completed NCT02378948 - Nutritional Route In Esophageal Resection Trial II N/A
Recruiting NCT02604615 - The Role of Different Cycles of Chemotherapy（Capecitabine-oxaliplatin） in Esophageal Chemoradiotherapy Phase 3