Clinical Trials Logo

Clinical Trial Summary

Chronic postsurgical pain has become one of the most common complications of surgery. The quality of life will be impacted once the postsurgical patients are combined with persistent pain. What's more, the postsurgical pain may increase other adverse outcomes. It's important to find a better way to keep the postsurgical patients away from postoperative pain. Esketamine and pregabalin have become potentially effective drugs on CPSP.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06117917
Study type Interventional
Source Beijing Tiantan Hospital
Contact Ruquan Han, M.D., Ph D
Phone 8610-59976660
Email ruquan.han@ccmu.edu.cn
Status Not yet recruiting
Phase Phase 2/Phase 3
Start date November 10, 2023
Completion date June 30, 2024

See also
  Status Clinical Trial Phase
Completed NCT05506787 - The Effects of Intraoperative Esketamine on Postoperative Pain and Mood in Patients With Inflammatory Bowel Disease Phase 4
Not yet recruiting NCT06062550 - Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia After Scoliosis Correction Surgery Phase 4
Recruiting NCT06003218 - Dexmedetomidine-esketamine for Percutaneous Radiofrequency Liver Ablation N/A
Recruiting NCT04664530 - The Study on the Esketamine in the Treatment of Postherpetic Neuralgia Phase 4
Recruiting NCT05718024 - Night-time Dexmedetomidine-esketamine Infusion and Sleep Quality With Mechanical Ventilation Phase 4
Recruiting NCT05950646 - Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality Phase 4
Recruiting NCT05732064 - Dexmedetomidine-esketamine Combined Nasal Administration and Perioperative Sleep Quality Phase 4
Not yet recruiting NCT06399185 - Effect of Dexmedetomidine and Esketamine on Catheter-related Bladder Discomfort Phase 4
Not yet recruiting NCT06389344 - Effect of Esketamine on Conscious State in Patients With pDoC N/A
Recruiting NCT04860661 - Esketamine on Postpartum Depression in Cesarean Section Women N/A
Completed NCT06398834 - Esketamine and Butorphanol for Post-Lobectomy Pain Phase 4
Completed NCT05458453 - An Exploratory Study of Esketamine in Patients After Thoracoscopic Surgery Phase 4
Recruiting NCT04843982 - Immunoinflammatory Regulation of Esketamine in Septic Patients Phase 4
Not yet recruiting NCT05943028 - Effect of Subanesthetic Dose Esketamine on Propofol-refentanil Closed-loop Targeted Controlled Infusion Early Phase 1
Active, not recruiting NCT05718544 - Mini-dose Esketamine-dexmedetomidine Supplemented Analgesia and Long-term Outcomes Phase 4
Not yet recruiting NCT06087510 - Different Dose Esketamine and Dexmedetomidine for Supplemental Analgesia and Longterm Outcomes Phase 4
Recruiting NCT06051227 - Fentanyl OR Esketamine for Traumatic PAIN (FORE-PAIN) Trial Phase 3
Recruiting NCT04425473 - Esketamine and Perioperative Depressive Symptoms Phase 2/Phase 3
Completed NCT05096468 - Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms. Phase 2/Phase 3
Not yet recruiting NCT04777110 - The Effectiveness and Safety of Esketamine in Modified Electroconvulsive Therapy Early Phase 1