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Erythema clinical trials

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NCT ID: NCT03584919 Completed - Clinical trials for Erythema Chronicum Migrans

Comparison of Doxycycline and Cefuroxime Axetil in Erythema Migrans

Start date: June 1, 2006
Phase: N/A
Study type: Interventional

A European, prospective clinical trial in which doxycycline and cefuroxime axetil were compared in the treatment of adult patients with erythema migrans included a control group to address this question. Evaluations of patients were conducted at baseline, 14 days and 2, 6, and 12 months after enrollment. Control subjects were evaluated at baseline and at 6 and 12 months. Subjective complaints that newly developed or intensified since the onset of erythema migrans or since the date of enrollment for controls were referred to as "new or increased symptoms"(NOIS).

NCT ID: NCT03549429 Completed - Erythema Clinical Trials

Tegaderm vs. EyeGard for Eye Protection

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

This study compares TegadermTM and EyeGard® in general anesthesia.

NCT ID: NCT03530787 Completed - Microbiome Clinical Trials

Cosmetic Effects of Topical Acetyl Zingerone

Start date: December 11, 2017
Phase: N/A
Study type: Interventional

Cosmeceuticals are an emerging market within dermatology and the growth of natural products and derivatives of natural products has accelerated in use within the field. Here the investigators aimed to study the microbial and cosmetic effects of Synoxyl AZ, the trade name for topical acetyl zingerone (AZ), a novel compound designed based on Zingerone and curcumin.

NCT ID: NCT03508869 Terminated - Clinical trials for Erythema and Flushing Associated With Rosacea

Mirvaso® Gel and Dysport® for Erythema and Flushing of Rosacea

Start date: September 27, 2016
Phase: N/A
Study type: Interventional

To evaluate the safety and efficacy of Mirvaso® Gel and Dysport® for erythema and flushing of Rosacea.

NCT ID: NCT03505879 Completed - Lyme Disease Clinical Trials

Next Generation Sequencing Detection of Lyme Disease

Start date: July 24, 2018
Phase:
Study type: Observational

Next Generation Sequencing is capable of sequencing millions of small strands of DNA from a single blood sample, potentially improving its sensitivity compared to PCR testing, which only detects predetermined larger strands of DNA. We will test the ability of NGS to detect Borrelia burgdorferi DNA in the blood of pediatric patients with Lyme disease. We will conduct an observational study of NGS testing on pediatric patients at all stages of Lyme disease. Study involvement will require a single study visit for clinical data collection and blood draw. We will enroll patients at all phases of suspected Lyme disease, collect clinically relevant information, and test for Lyme disease using Next Generation Sequencing and standard Lyme serologic testing. If the patient has multiple erythema migrans, Lyme meningitis, facial nerve palsy, arthritis, or carditis, a B. burgdorferi serum PCR will also be sent. Enrollment and Next Generation Sequencing blood draw will occur before or up to 24 hours after the first dose of antibiotics is administered. We will also study the impact of antibiotics on NGS testing by running the test 6-24 hours after antibiotics are started among a small subset of patients with a multiple erythema migrans rash. Collected data will be analyzed with basic descriptive statistics.

NCT ID: NCT03496584 Terminated - Inflammation Clinical Trials

Effects of Phytonutrients on Vascular Health and Skin in Obese Males

PomSkin
Start date: March 29, 2018
Phase: N/A
Study type: Interventional

This study will determine the effects of beneficial compounds of plant foods, such as pomegranate on cardiovascular health, skin inflammation and aging. This will be tested by asking healthy males to eat a high fat ground beef patty with 8oz. pomegranate juice or 8oz placebo (a study product that looks like pomegranate juice, but contains no active ingredients) and then measuring blood vessel dilation (endothelial function) by blood flow. The investigators also will measure the amount of Nitric Oxide (NO) in blood and urine samples and sugar and insulin in blood. In addition, a Cutometer, a device that measures the elasticity of the skin, will be used to obtain measurements of skin inflammation and aging. Healthy men have been chosen for this study because eating high fat hamburger patties can easily mimic in them the condition that causes atherosclerosis. The results from this study may help to explain how high fat foods can be harmful to the body and how beneficial plant foods can have on cardiovascular function and the skin.

NCT ID: NCT03477825 Completed - Wrinkles Clinical Trials

Pilot Study of Triphala and Rubia Cordifolia on Gut Microbiome and Skin

Start date: March 12, 2018
Phase: N/A
Study type: Interventional

Few studies have assessed the effects of Triphala and Rubia Cordifolia from a skin biophysical perspective. Here, we aim to understand how these herbs can modulate the skin's barrier properties and the gut microbiome.

NCT ID: NCT03462329 Recruiting - Erythema Migrans Clinical Trials

Patient's Pretreatment Expectations About Post-Lyme Symptoms

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

The investigators will focus on pretreatment expectations of patients with early Lyme disease manifested as erythema migrans with the aim of assessing the association between pretreatment expectations quantified with a questionnaire and treatment outcome quantified with the presence of post-Lyme symptoms. Furthermore, the investigators will compare the prevalence of nonspecific symptoms among patients and among age-matched controls without a history of Lyme borreliosis.

NCT ID: NCT03455036 Completed - Itch; Athlete Clinical Trials

The Mysterious on/Off Itch and Erythema During Whole Body Vibration Exercise

VIBRA
Start date: December 18, 2017
Phase: N/A
Study type: Interventional

Intense itch on the legs sometimes associated with redness can be adverse effects of whole body vibration (WBV) according to own observations and numerous posts in non-professional online-blogs. To the investigators' knowledge, the appearance of itch and/or a rash during WBV exercise has not yet been described. The research objectives are: 1. To determine the effect of WBV on itch rating and its unpleasantness and on skin changes. 2. To determine the effect of WBV on immunoglobulin E (IgE) and serum tryptase

NCT ID: NCT03371563 Completed - Lyme Disease Clinical Trials

Erythema Migrans in Elderly

Start date: January 1, 2006
Phase:
Study type: Observational [Patient Registry]

The investigators will focus on elderly patients with early Lyme borreliosis with the aim of assessing clinical course, serological response and treatment outcome of the disease as compared to younger adults. Furthermore, the investigators will compare the prevalence of nonspecific symptoms among patients and among age-matched controls without a history of Lyme borreliosis.