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Epistaxis clinical trials

View clinical trials related to Epistaxis.

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NCT ID: NCT05343650 Not yet recruiting - Epistaxis Clinical Trials

NOVAPAK Nasal Packing in Shellfish Allergic Patients

Start date: March 15, 2024
Phase: Phase 4
Study type: Interventional

NOVAPAK is a sponge-like material made from materials found in shellfish. It is commonly used after nasal surgery or in nasal bleeding, as it promotes healing, decreases bleeding, and has antibacterial properties. Although NOVOPAK does not contain proteins or compounds known to be responsible for allergic reactions in people with a known allergy to shellfish, out of an abundance of caution, the manufacturer (Medtronic) has recommended avoidance in those with known shellfish allergy. There have been no reported allergic reactions in patients with shellfish allergy who were given chitosan bandages in emergencies (e.g. military applications). The study aims to investigate the safety of its use in patients with known shellfish allergy to improve healthcare quality and patient care support.

NCT ID: NCT05072392 Not yet recruiting - Nasal Bleeding Clinical Trials

Determining the Effects of Foley Catheter-assisted Nasal Intubation on Nasal Bleeding in Adult Patients

Start date: October 4, 2021
Phase: N/A
Study type: Interventional

Nasal endotracheal intubation is a well-utilized and important endotracheal intubation route to allow good surgical access for operations involving the oral cavity. Despite its utility, there are potential complications from nasal endotracheal intubation including that of nasal bleeding, which in severe cases can impair the ability to complete the procedure. The most accepted conventional practice to decrease bleeding associated with nasal endotracheal intubation is to warm the nasal endotracheal tube prior to insertion. However, this technique still yields high rates of nasal bleeding. In 1979, correspondence by MacKinnon and Harrison in Anaesthesia described the use of a flexible urinary catheter (Foley catheter) telescoped onto the endotracheal tube tip to aid atraumatic insertion of the tube. This also served to ensure the tube was not contaminated internally by nasal secretions or blood. This has been more rigorously studied in two RCTs looking at this technique in children, but there has been no similar study in adults. This study aims to extend the evidence base of the use of this technique in adults. Our hypothesis is that the use of a flexible urinary catheter to telescopically aid nasal intubation will result in a significant decrease in the incidence and severity of nasal bleeding.

NCT ID: NCT04519463 Not yet recruiting - Analgesia Clinical Trials

The Effect of Local Anesthesia With Lidocaine During Insertion and Removal of Nasal Packing

Start date: September 2020
Phase: Early Phase 1
Study type: Interventional

This study aims to investigate the effect of local nasal anesthesia with lidocaine spray on the insertion of nasal tampons during active nasal bleeding.

NCT ID: NCT04374448 Not yet recruiting - Chronic Sinusitis Clinical Trials

Utility of Indocyanine Green Fluorescence in Endoscopic Sinonasal and Skull Base Surgery

NIRFICG
Start date: January 1, 2023
Phase: N/A
Study type: Interventional

The endoscope is a device placed into the nasal cavity to remove chronic sinus disease or tumor or create access into the skullbase for extensive tumor removal. Indocyanine Green (ICG) is a dye that is injected through an intravenous site and is used to light up vasculature and margins of a tumor during surgery. This helps avoid damage to important vasculature and obtain clear margins during surgery. This study aims to further assess the utility of ICG when operating within the nasal cavity or skullbase.

NCT ID: NCT04151888 Not yet recruiting - Epistaxis Clinical Trials

Hot Water Irrigation in Posterior Epistaxis

Start date: January 30, 2020
Phase:
Study type: Observational

This study was aimed to assess the efficacy and factors affecting the success of hot water irrigation in management of posterior epistaxis.

NCT ID: NCT03850730 Not yet recruiting - Epistaxis Clinical Trials

Pazopanib for the Treatment of Epistaxis in Hereditary Hemorrhagic Telangiectasia

Start date: July 1, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

Investigators will test the value of very low dose Pazopanib administered to patients with hereditary hemorrhagic telangiectasia for the reduction in the severity of nose bleeds in those with frequent and long duration bleeding episodes.

NCT ID: NCT03788460 Not yet recruiting - Epistaxis Clinical Trials

Correlation Between PT and INR to Factor 7

Start date: January 7, 2019
Phase:
Study type: Observational

The purpose of our study: Given the large number of coagulability tests done before a number of surgeries, specially otolaryngology procedures, such as tonsillectomy and adenoidectomy, as well as a part of epistaxis workup, prothrombin time (PT) and partial thromboplastin time (PTT) were checked, and it was found that in some people there is an isolated elongated PT, a low level of factor VII was found in these people. The purpose of the current study is to find a correlation between the value of PT\INR and the level of factor VII, we tried to do so by a retro-prospective study on patients known to have a factor VII deficiency at Laniado hospital, such a correlation could make both the diagnosis and the management of people with factor VII deficiency easier and more accessible. The study levels: 1. Data collection : On the children's population who are known for their lack of Factor VII, we will check PT levels, we will concentrate the data in the table, along with personal information such as age and gender 2. Data Processing : We will try to conduct a statistical relationship between the PT values and Factor VII levels, to look for statistical significance, we will try to find a model for predicting the level of factor VII based on PT Number of participants: 60 participants Ages of participants: 0-18 years old Gender of participants: Both sexes Inclusion criteria: 1. A participant who is 0-18 years old 2. A participant who is, except for bleeding tendency, healthy in general 3. A participant who has elongated PT 4. A participant who has normal PTT Exclusion criteria: 1. Background disease 2. Use of medications 3. Use of anti coagulation drugs The duration of the study : The study is of a retrospective type, we already have a number of subjects, we need more as to reach statistical significance, so the expectation is two to three months

NCT ID: NCT02963129 Not yet recruiting - Epistaxis Clinical Trials

Treatment of Nasal Staphylococcus Aureus Colonization in Patients With HHT

Start date: June 2017
Phase: Phase 3
Study type: Interventional

Compare the frequency of epistaxis and quality of life related to nasal bleeding in patients with HHT colonized with sataphylococo before and after being treated with mupirocin ointment.

NCT ID: NCT02677467 Not yet recruiting - Clinical trials for Cardiovascular Disease

Correlation Between Epistaxis and Cardiovascular Disease

CBECD
Start date: March 2016
Phase: N/A
Study type: Observational [Patient Registry]

Investigators examine blood-pressure variance, several cardiovascular risk factors of patient with epistaxis. As a result of collected data, investigators look into correlation between epistaxis and hypertensive cardiovascular disorder.